Zn:Cr Mixed Oxide Catalyzed Facile Construction of 4-Aryl-6-(3-Coumarinyl)Pyrimidin-2(1H)-Ones Derivatives under the Solvent-Free Condition

Md Afroz Bakht; Mshari Alotaibi; Abdulrahman I. Alharthi; Mohamed H. Geesi; Israf Ud Din; Mohd Imran; Hamdy Khamees Thabet

doi:10.1080/10406638.2021.1924800

Zn:Cr Mixed Oxide Catalyzed Facile Construction of 4-Aryl-6-(3-Coumarinyl)Pyrimidin-2(1H)-Ones Derivatives under the Solvent-Free Condition

Md Afroz Bakht, Mshari Alotaibi, Abdulrahman I. Alharthi, Mohamed H. Geesi, Israf Ud Din, Mohd Imran, Hamdy Khamees Thabet

Chemistry

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1 Scopus citations

Abstract

Zn:Cr mixed oxide catalyst was examined as an effective and recyclable catalyst for the synthesis selected pyrimidine derivatives in high yield. The catalyst was characterized by FT-IR, XRD, BET, SEM, EDX and Zeta potential analysis. Substituted 4-aryl-6-(3-coumarinyl) pyrimidine-2(1H)-ones were prepared in high yield and purity via the cyclocondensation of urea and 3-acetylcoumarin with substituted aldehydes in the presence of a catalytic amount of Zn:Cr mixed oxide catalyst as Lewis acid at ambient temperature. The effect of the molar ratio of the catalyst was also studied, and as a result, Zn:Cr (10:1) showed better catalytic performance than Zn:Cr (1:1) at identical reaction conditions. Furthermore, catalyst stability was intact as confirmed by the catalyst recyclability experiment.

Original language	English
Pages (from-to)	4922-4936
Number of pages	15
Journal	Polycyclic Aromatic Compounds
Volume	42
Issue number	8
DOIs	https://doi.org/10.1080/10406638.2021.1924800
State	Published - 2022

Keywords

Coumarin
mixed oxide catalyst
pyrimidine
solvent-free
zinc-chromium

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10.1080/10406638.2021.1924800

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title = "Zn:Cr Mixed Oxide Catalyzed Facile Construction of 4-Aryl-6-(3-Coumarinyl)Pyrimidin-2(1H)-Ones Derivatives under the Solvent-Free Condition",

abstract = "Zn:Cr mixed oxide catalyst was examined as an effective and recyclable catalyst for the synthesis selected pyrimidine derivatives in high yield. The catalyst was characterized by FT-IR, XRD, BET, SEM, EDX and Zeta potential analysis. Substituted 4-aryl-6-(3-coumarinyl) pyrimidine-2(1H)-ones were prepared in high yield and purity via the cyclocondensation of urea and 3-acetylcoumarin with substituted aldehydes in the presence of a catalytic amount of Zn:Cr mixed oxide catalyst as Lewis acid at ambient temperature. The effect of the molar ratio of the catalyst was also studied, and as a result, Zn:Cr (10:1) showed better catalytic performance than Zn:Cr (1:1) at identical reaction conditions. Furthermore, catalyst stability was intact as confirmed by the catalyst recyclability experiment.",

keywords = "Coumarin, mixed oxide catalyst, pyrimidine, solvent-free, zinc-chromium",

author = "Bakht, \{Md Afroz\} and Mshari Alotaibi and Alharthi, \{Abdulrahman I.\} and Geesi, \{Mohamed H.\} and \{Ud Din\}, Israf and Mohd Imran and Thabet, \{Hamdy Khamees\}",

note = "Publisher Copyright: {\textcopyright} 2021 Taylor \& Francis Group, LLC.",

year = "2022",

doi = "10.1080/10406638.2021.1924800",

language = "English",

volume = "42",

pages = "4922--4936",

journal = "Polycyclic Aromatic Compounds",

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TY - JOUR

T1 - Zn:Cr Mixed Oxide Catalyzed Facile Construction of 4-Aryl-6-(3-Coumarinyl)Pyrimidin-2(1H)-Ones Derivatives under the Solvent-Free Condition

AU - Bakht, Md Afroz

AU - Alotaibi, Mshari

AU - Alharthi, Abdulrahman I.

AU - Geesi, Mohamed H.

AU - Ud Din, Israf

AU - Imran, Mohd

AU - Thabet, Hamdy Khamees

PY - 2022

Y1 - 2022

N2 - Zn:Cr mixed oxide catalyst was examined as an effective and recyclable catalyst for the synthesis selected pyrimidine derivatives in high yield. The catalyst was characterized by FT-IR, XRD, BET, SEM, EDX and Zeta potential analysis. Substituted 4-aryl-6-(3-coumarinyl) pyrimidine-2(1H)-ones were prepared in high yield and purity via the cyclocondensation of urea and 3-acetylcoumarin with substituted aldehydes in the presence of a catalytic amount of Zn:Cr mixed oxide catalyst as Lewis acid at ambient temperature. The effect of the molar ratio of the catalyst was also studied, and as a result, Zn:Cr (10:1) showed better catalytic performance than Zn:Cr (1:1) at identical reaction conditions. Furthermore, catalyst stability was intact as confirmed by the catalyst recyclability experiment.

AB - Zn:Cr mixed oxide catalyst was examined as an effective and recyclable catalyst for the synthesis selected pyrimidine derivatives in high yield. The catalyst was characterized by FT-IR, XRD, BET, SEM, EDX and Zeta potential analysis. Substituted 4-aryl-6-(3-coumarinyl) pyrimidine-2(1H)-ones were prepared in high yield and purity via the cyclocondensation of urea and 3-acetylcoumarin with substituted aldehydes in the presence of a catalytic amount of Zn:Cr mixed oxide catalyst as Lewis acid at ambient temperature. The effect of the molar ratio of the catalyst was also studied, and as a result, Zn:Cr (10:1) showed better catalytic performance than Zn:Cr (1:1) at identical reaction conditions. Furthermore, catalyst stability was intact as confirmed by the catalyst recyclability experiment.

KW - Coumarin

KW - mixed oxide catalyst

KW - pyrimidine

KW - solvent-free

KW - zinc-chromium

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U2 - 10.1080/10406638.2021.1924800

DO - 10.1080/10406638.2021.1924800

M3 - Article

AN - SCOPUS:85106317989

SN - 1040-6638

VL - 42

SP - 4922

EP - 4936

JO - Polycyclic Aromatic Compounds

JF - Polycyclic Aromatic Compounds

IS - 8

ER -

Zn:Cr Mixed Oxide Catalyzed Facile Construction of 4-Aryl-6-(3-Coumarinyl)Pyrimidin-2(1H)-Ones Derivatives under the Solvent-Free Condition

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Keywords

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