Wound healing effects of nanoemulsion containing clove essential oil

Prawez Alam; Mohammad Javed Ansari; Md Khalid Anwer; Mohammad Raish; Yoonus K.T. Kamal; Faiyaz Shakeel

doi:10.3109/21691401.2016.1163716

Wound healing effects of nanoemulsion containing clove essential oil

Prawez Alam, Mohammad Javed Ansari, Md Khalid Anwer, Mohammad Raish, Yoonus K.T. Kamal, Faiyaz Shakeel

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90 Scopus citations

Abstract

The aim of this study was to investigate the wound healing effects of clove oil (CO) via its encapsulation into nanoemulsion. Optimized nanoemulsion (droplet size of 29.10 nm) was selected for wound healing investigation, collagen determination, and histopathological examination in rats. Optimized nanoemulsion presented significant would healing effects in rats as compared to pure CO. Nanoemulsion also presented significant enhancement in leucine content (0.61 mg/g) as compared to pure CO (0.50 mg/g) and negative control (0.31 mg/g). Histopathology of nanoemulsion treated rats showed no signs of inflammatory cells. These results suggested that nanoemulsion of CO was safe and nontoxic.

Original language	English
Pages (from-to)	591-597
Number of pages	7
Journal	Artificial Cells, Nanomedicine and Biotechnology
Volume	45
Issue number	3
DOIs	https://doi.org/10.3109/21691401.2016.1163716
State	Published - 3 Apr 2017

Keywords

Clove oil
collagen
histopathology
leucine
nanoemulsion
wound healing

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10.3109/21691401.2016.1163716

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title = "Wound healing effects of nanoemulsion containing clove essential oil",

abstract = "The aim of this study was to investigate the wound healing effects of clove oil (CO) via its encapsulation into nanoemulsion. Optimized nanoemulsion (droplet size of 29.10 nm) was selected for wound healing investigation, collagen determination, and histopathological examination in rats. Optimized nanoemulsion presented significant would healing effects in rats as compared to pure CO. Nanoemulsion also presented significant enhancement in leucine content (0.61 mg/g) as compared to pure CO (0.50 mg/g) and negative control (0.31 mg/g). Histopathology of nanoemulsion treated rats showed no signs of inflammatory cells. These results suggested that nanoemulsion of CO was safe and nontoxic.",

keywords = "Clove oil, collagen, histopathology, leucine, nanoemulsion, wound healing",

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AU - Alam, Prawez

AU - Javed Ansari, Mohammad

AU - Anwer, Md Khalid

AU - Raish, Mohammad

AU - Kamal, Yoonus K.T.

AU - Shakeel, Faiyaz

PY - 2017/4/3

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AB - The aim of this study was to investigate the wound healing effects of clove oil (CO) via its encapsulation into nanoemulsion. Optimized nanoemulsion (droplet size of 29.10 nm) was selected for wound healing investigation, collagen determination, and histopathological examination in rats. Optimized nanoemulsion presented significant would healing effects in rats as compared to pure CO. Nanoemulsion also presented significant enhancement in leucine content (0.61 mg/g) as compared to pure CO (0.50 mg/g) and negative control (0.31 mg/g). Histopathology of nanoemulsion treated rats showed no signs of inflammatory cells. These results suggested that nanoemulsion of CO was safe and nontoxic.

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Wound healing effects of nanoemulsion containing clove essential oil

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