Virtual reality modulating dynamics of neuroplasticity: Innovations in neuro-motor rehabilitation

Nitu L. Wankhede, Sushruta Koppula, Suhas Ballal, Hardik Doshi, Rohit Kumawat, SSrinadh S. Raju, Isha Arora, Shivkumar S. Sammeta, Mohammad Khalid, Ameeduzzafar Zafar, Brijesh G. Taksande, Aman B. Upaganlawar, Monica Gulati, Milind J. Umekar, Spandana Rajendra Kopalli, Mayur B. Kale

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

Virtual reality (VR) technology has emerged as a ground-breaking tool in neuroscience, revolutionizing our understanding of neuroplasticity and its implications for neurological rehabilitation. By immersing individuals in simulated environments, VR induces profound neurobiological transformations, affecting neuronal connectivity, sensory feedback mechanisms, motor learning processes, and cognitive functions. These changes highlight the dynamic interplay between molecular events, synaptic adaptations, and neural reorganization, emphasizing the potential of VR as a therapeutic intervention in various neurological disorders. This comprehensive review delves into the therapeutic applications of VR, focusing on its role in addressing multiple conditions such as stroke, traumatic brain injuries, phobias, and post-traumatic stress disorder. It highlights how VR can enhance motor recovery, cognitive rehabilitation, and emotional resilience, showcasing its potential as an innovative and effective tool in neurological rehabilitation. Integrating molecular neuroscience with VR technology allows for a deeper understanding of the molecular mechanisms underlying neuroplasticity, opening doors to personalized interventions and precise treatment strategies for individuals with neurological impairments. Moreover, the review emphasizes the ethical considerations and challenges that come with implementing VR-based interventions in clinical practice, stressing the importance of data privacy, informed consent, and collaborative interdisciplinary efforts. By leveraging advanced molecular imaging techniques, VR-based research methodologies, and computational modelling, the review envisions a future where VR technology plays a central role in revolutionizing neuroscience research and clinical neurorehabilitation, ultimately providing tailored and impactful solutions for individuals facing neurological challenges.

Original languageEnglish
Pages (from-to)97-111
Number of pages15
JournalNeuroscience
Volume566
DOIs
StatePublished - 6 Feb 2025

Keywords

  • Molecular neuroscience
  • Neuroplasticity
  • Neurorehabilitation
  • Therapeutic applications
  • Virtual reality

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