TY - JOUR
T1 - Virtual reality modulating dynamics of neuroplasticity
T2 - Innovations in neuro-motor rehabilitation
AU - Wankhede, Nitu L.
AU - Koppula, Sushruta
AU - Ballal, Suhas
AU - Doshi, Hardik
AU - Kumawat, Rohit
AU - Raju, SSrinadh S.
AU - Arora, Isha
AU - Sammeta, Shivkumar S.
AU - Khalid, Mohammad
AU - Zafar, Ameeduzzafar
AU - Taksande, Brijesh G.
AU - Upaganlawar, Aman B.
AU - Gulati, Monica
AU - Umekar, Milind J.
AU - Kopalli, Spandana Rajendra
AU - Kale, Mayur B.
N1 - Publisher Copyright:
© 2024 International Brain Research Organization (IBRO)
PY - 2025/2/6
Y1 - 2025/2/6
N2 - Virtual reality (VR) technology has emerged as a ground-breaking tool in neuroscience, revolutionizing our understanding of neuroplasticity and its implications for neurological rehabilitation. By immersing individuals in simulated environments, VR induces profound neurobiological transformations, affecting neuronal connectivity, sensory feedback mechanisms, motor learning processes, and cognitive functions. These changes highlight the dynamic interplay between molecular events, synaptic adaptations, and neural reorganization, emphasizing the potential of VR as a therapeutic intervention in various neurological disorders. This comprehensive review delves into the therapeutic applications of VR, focusing on its role in addressing multiple conditions such as stroke, traumatic brain injuries, phobias, and post-traumatic stress disorder. It highlights how VR can enhance motor recovery, cognitive rehabilitation, and emotional resilience, showcasing its potential as an innovative and effective tool in neurological rehabilitation. Integrating molecular neuroscience with VR technology allows for a deeper understanding of the molecular mechanisms underlying neuroplasticity, opening doors to personalized interventions and precise treatment strategies for individuals with neurological impairments. Moreover, the review emphasizes the ethical considerations and challenges that come with implementing VR-based interventions in clinical practice, stressing the importance of data privacy, informed consent, and collaborative interdisciplinary efforts. By leveraging advanced molecular imaging techniques, VR-based research methodologies, and computational modelling, the review envisions a future where VR technology plays a central role in revolutionizing neuroscience research and clinical neurorehabilitation, ultimately providing tailored and impactful solutions for individuals facing neurological challenges.
AB - Virtual reality (VR) technology has emerged as a ground-breaking tool in neuroscience, revolutionizing our understanding of neuroplasticity and its implications for neurological rehabilitation. By immersing individuals in simulated environments, VR induces profound neurobiological transformations, affecting neuronal connectivity, sensory feedback mechanisms, motor learning processes, and cognitive functions. These changes highlight the dynamic interplay between molecular events, synaptic adaptations, and neural reorganization, emphasizing the potential of VR as a therapeutic intervention in various neurological disorders. This comprehensive review delves into the therapeutic applications of VR, focusing on its role in addressing multiple conditions such as stroke, traumatic brain injuries, phobias, and post-traumatic stress disorder. It highlights how VR can enhance motor recovery, cognitive rehabilitation, and emotional resilience, showcasing its potential as an innovative and effective tool in neurological rehabilitation. Integrating molecular neuroscience with VR technology allows for a deeper understanding of the molecular mechanisms underlying neuroplasticity, opening doors to personalized interventions and precise treatment strategies for individuals with neurological impairments. Moreover, the review emphasizes the ethical considerations and challenges that come with implementing VR-based interventions in clinical practice, stressing the importance of data privacy, informed consent, and collaborative interdisciplinary efforts. By leveraging advanced molecular imaging techniques, VR-based research methodologies, and computational modelling, the review envisions a future where VR technology plays a central role in revolutionizing neuroscience research and clinical neurorehabilitation, ultimately providing tailored and impactful solutions for individuals facing neurological challenges.
KW - Molecular neuroscience
KW - Neuroplasticity
KW - Neurorehabilitation
KW - Therapeutic applications
KW - Virtual reality
UR - http://www.scopus.com/inward/record.url?scp=85214272512&partnerID=8YFLogxK
U2 - 10.1016/j.neuroscience.2024.12.040
DO - 10.1016/j.neuroscience.2024.12.040
M3 - Review article
C2 - 39722287
AN - SCOPUS:85214272512
SN - 0306-4522
VL - 566
SP - 97
EP - 111
JO - Neuroscience
JF - Neuroscience
ER -