Titanium Dioxide/Chromium Oxide/Graphene Oxide Doped into Cellulose Acetate for Medical Applications

Latifah Mohammed Ali Almaieli, Mai M. Khalaf, Mohamed Gouda, Sultan Alhayyani, Manal F. Abou Taleb, Hany M. Abd El-Lateef

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Wound dressings have been designed based on cellulose acetate encapsulated with different concentrations of chromium oxide (Cr2O3) and titanium oxide (TiO2) with/without graphene oxide (GO). This study comprises the structural, morphological, optical, thermal, and biological behavior of chromium oxide/titanium dioxide/graphene oxide-integrated cellulose acetate (CA) films. The CA-based film bond formation was introduced by functional group analysis via Fourier transform infrared (FTIR) spectroscopy. The fabricated Cr2O3/TiO2/GO@CA film SEM micrographs demonstrate transition metal oxides Cr2O3 and TiO2 on a nano-scale. The TiO2@CA shows the lowest contact angle with 30°. Optically, the refractive index increases from 1.76 for CA to 2.14 for the TiO2@CA film. Moreover, normal lung cells (A138) growth examination in a function of Cr2O3/TiO2/GO@CA film concentration is conducted, introducing 93.46% with the usage of 4.9 µg/mL. The resulting data showed a promising wound-healing behavior of the CA-based films.

Original languageEnglish
Article number485
JournalPolymers
Volume15
Issue number3
DOIs
StatePublished - Feb 2023

Keywords

  • cell viability
  • CrO
  • GO
  • TiO
  • wound healing

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