TY - JOUR
T1 - The role of chromium supplementation in cardiovascular risk factors
T2 - A comprehensive reviews of putative molecular mechanisms
AU - Gossa Al-Saadde, Dhiaa lattef
AU - Haider, Ali Murtaza
AU - Ali, Arsalan
AU - Abdu Musad Saleh, Ebraheem
AU - Turki Jalil, Abduladheem
AU - Abdulelah, Furqan M.
AU - Romero-Parra, Rosario Mireya
AU - Tayyib, Nahla A.
AU - Ramírez-Coronel, Andrés Alexis
AU - Alkhayyat, Ameer S.
N1 - Publisher Copyright:
© 2023 The Authors
PY - 2023/9
Y1 - 2023/9
N2 - In the recent years, micronutrients play an important role in improving body health with preventing and treating of chronic diseases. Chromium is one of the vital minerals involved in the regulation of insulin action. According to abundant evidences this mineral seems to be an essential factor involved in the reduction of insulin resistance and decreasing the risk of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVDs). Moreover, it has been proposed that Chromium supplementation affects mechanisms involved in blood pressure, lipid metabolism, inflammation, and oxidative stress. For instance, it may affect blood pressure through alteration of the renin-angiotensin system, as well as reducing the angiotensin-converting enzyme activity. Furthermore, Chromium supplementation might help reduce the coronary heart disease rates. This study aims to provide a comprehensive review regarding to the effects of Chromium supplementation on CVDs risk factors with an emphasis on possible molecular mechanisms.
AB - In the recent years, micronutrients play an important role in improving body health with preventing and treating of chronic diseases. Chromium is one of the vital minerals involved in the regulation of insulin action. According to abundant evidences this mineral seems to be an essential factor involved in the reduction of insulin resistance and decreasing the risk of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVDs). Moreover, it has been proposed that Chromium supplementation affects mechanisms involved in blood pressure, lipid metabolism, inflammation, and oxidative stress. For instance, it may affect blood pressure through alteration of the renin-angiotensin system, as well as reducing the angiotensin-converting enzyme activity. Furthermore, Chromium supplementation might help reduce the coronary heart disease rates. This study aims to provide a comprehensive review regarding to the effects of Chromium supplementation on CVDs risk factors with an emphasis on possible molecular mechanisms.
KW - Cardiovascular diseases
KW - Chromium
KW - Hypertension
KW - Inflammation
KW - Oxidative stress
UR - http://www.scopus.com/inward/record.url?scp=85170715536&partnerID=8YFLogxK
U2 - 10.1016/j.heliyon.2023.e19826
DO - 10.1016/j.heliyon.2023.e19826
M3 - Review article
AN - SCOPUS:85170715536
SN - 2405-8440
VL - 9
JO - Heliyon
JF - Heliyon
IS - 9
M1 - e19826
ER -
