Synthesis of novel functionally substituted pyridazines and oxazines

M. Hammouda; Z. M. Abou Zeid; M. A. Metwally

doi:10.1007/s10593-008-0141-2

Synthesis of novel functionally substituted pyridazines and oxazines

M. Hammouda
, Z. M. Abou Zeid
, M. A. Metwally

Mansoura University

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Acetone 1,3-di(phenylhydrazone) reacts with arylidenemalononitriles in the presence of piperidine to give the coressponding 3,3′- carbonylbispyridazine derivatives. Under the same reaction conditions dioxime reacts with arylidenemalononitriles to give the corresponding 3,3′-carbonylbis-1,2-oxazines. Dioxime reacts with primary aromatic amines and formalin in a molar ratio of 1:1:2 to give 1-arylidene-3,5-dihydroxyimino- piperidine-4-ones.

Original language	English
Pages (from-to)	985-990
Number of pages	6
Journal	Chemistry of Heterocyclic Compounds
Volume	44
Issue number	8
DOIs	https://doi.org/10.1007/s10593-008-0141-2
State	Published - Aug 2008
Externally published	Yes

Keywords

Acetone 1,3-dioxime,acetone 1,3-diphenylhydrazone,1,2-dioximes
Pyridazines

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10.1007/s10593-008-0141-2

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title = "Synthesis of novel functionally substituted pyridazines and oxazines",

abstract = "Acetone 1,3-di(phenylhydrazone) reacts with arylidenemalononitriles in the presence of piperidine to give the coressponding 3,3′- carbonylbispyridazine derivatives. Under the same reaction conditions dioxime reacts with arylidenemalononitriles to give the corresponding 3,3′-carbonylbis-1,2-oxazines. Dioxime reacts with primary aromatic amines and formalin in a molar ratio of 1:1:2 to give 1-arylidene-3,5-dihydroxyimino- piperidine-4-ones.",

keywords = "Acetone 1,3-dioxime,acetone 1,3-diphenylhydrazone,1,2-dioximes, Pyridazines",

author = "M. Hammouda and \{Abou Zeid\}, \{Z. M.\} and Metwally, \{M. A.\}",

year = "2008",

month = aug,

doi = "10.1007/s10593-008-0141-2",

language = "English",

volume = "44",

pages = "985--990",

journal = "Chemistry of Heterocyclic Compounds",

issn = "0009-3122",

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T1 - Synthesis of novel functionally substituted pyridazines and oxazines

AU - Hammouda, M.

AU - Abou Zeid, Z. M.

AU - Metwally, M. A.

PY - 2008/8

Y1 - 2008/8

N2 - Acetone 1,3-di(phenylhydrazone) reacts with arylidenemalononitriles in the presence of piperidine to give the coressponding 3,3′- carbonylbispyridazine derivatives. Under the same reaction conditions dioxime reacts with arylidenemalononitriles to give the corresponding 3,3′-carbonylbis-1,2-oxazines. Dioxime reacts with primary aromatic amines and formalin in a molar ratio of 1:1:2 to give 1-arylidene-3,5-dihydroxyimino- piperidine-4-ones.

AB - Acetone 1,3-di(phenylhydrazone) reacts with arylidenemalononitriles in the presence of piperidine to give the coressponding 3,3′- carbonylbispyridazine derivatives. Under the same reaction conditions dioxime reacts with arylidenemalononitriles to give the corresponding 3,3′-carbonylbis-1,2-oxazines. Dioxime reacts with primary aromatic amines and formalin in a molar ratio of 1:1:2 to give 1-arylidene-3,5-dihydroxyimino- piperidine-4-ones.

KW - Acetone 1,3-dioxime,acetone 1,3-diphenylhydrazone,1,2-dioximes

KW - Pyridazines

UR - https://www.scopus.com/pages/publications/56749161529

U2 - 10.1007/s10593-008-0141-2

DO - 10.1007/s10593-008-0141-2

M3 - Article

AN - SCOPUS:56749161529

SN - 0009-3122

VL - 44

SP - 985

EP - 990

JO - Chemistry of Heterocyclic Compounds

JF - Chemistry of Heterocyclic Compounds

IS - 8

ER -

Synthesis of novel functionally substituted pyridazines and oxazines

Abstract

Keywords

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