TY - JOUR
T1 - Synthesis of alkaline protease modified ALPs-V2O5/MCM-41 nanocomposite and their multifunctional applications as an efficient photocatalytic, antibacterial and DPPH radicals stabilizing agent
AU - Rehman, Khalil ur
AU - Zghab, Imen
AU - Alissa, Mohammed
AU - Tahir, Kamran
AU - Hajri, Amira K.
AU - Zouidi, Ferjeni
AU - Alghamdi, Abdullah
AU - Alghamdi, Suad A.
AU - Alshehri, Mohammed A.
AU - Alhegaili, Alaa S.
N1 - Publisher Copyright:
© 2025 Taiwan Institute of Chemical Engineers
PY - 2025/7
Y1 - 2025/7
N2 - Background: The development of eco-friendly and sustainable nanomaterials is crucial for environmental safety and biomedical applications. This study presents a novel approach to synthesizing vanadium oxide-doped MCM-41 nanocomposites (V₂O₅/MCM-41) using an alkaline protease (ALPs) extracted from Phalaris minor seeds. Method: The ALPs-assisted synthesis method was employed for the first time to fabricate V₂O₅/MCM-41 nanocomposites, and their physicochemical properties were characterized to determine size, morphology, and crystallinity. Significant findings: The synthesized ALPs-V₂O₅/MCM-41 nanocomposites exhibited outstanding photocatalytic performance, achieving 97 % degradation of bromothymol blue (BTB) within 50 min of irradiation. Additionally, the synthesized nanocomposites exhibited strong antibacterial properties against Escherichia coli and Staphylococcus aureus, with inhibition zones measuring between 22(±0.3) mm and 31(±0.4) mm under both illuminated and non-illuminated conditions. Moreover, they exhibited remarkable antioxidant properties, with an 88 % scavenging efficacy against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals. Conclusion: These findings highlight the potential of ALPs-V₂O₅/MCM-41 nanocomposites as a sustainable and multifunctional material for environmental remediation and antimicrobial applications, paving the way for further research in eco-friendly nanotechnology.
AB - Background: The development of eco-friendly and sustainable nanomaterials is crucial for environmental safety and biomedical applications. This study presents a novel approach to synthesizing vanadium oxide-doped MCM-41 nanocomposites (V₂O₅/MCM-41) using an alkaline protease (ALPs) extracted from Phalaris minor seeds. Method: The ALPs-assisted synthesis method was employed for the first time to fabricate V₂O₅/MCM-41 nanocomposites, and their physicochemical properties were characterized to determine size, morphology, and crystallinity. Significant findings: The synthesized ALPs-V₂O₅/MCM-41 nanocomposites exhibited outstanding photocatalytic performance, achieving 97 % degradation of bromothymol blue (BTB) within 50 min of irradiation. Additionally, the synthesized nanocomposites exhibited strong antibacterial properties against Escherichia coli and Staphylococcus aureus, with inhibition zones measuring between 22(±0.3) mm and 31(±0.4) mm under both illuminated and non-illuminated conditions. Moreover, they exhibited remarkable antioxidant properties, with an 88 % scavenging efficacy against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals. Conclusion: These findings highlight the potential of ALPs-V₂O₅/MCM-41 nanocomposites as a sustainable and multifunctional material for environmental remediation and antimicrobial applications, paving the way for further research in eco-friendly nanotechnology.
KW - ALPs-VO/MCM-41 nanocomposite
KW - Alkaline protease
KW - Photocatalytic activity
UR - http://www.scopus.com/inward/record.url?scp=105002690264&partnerID=8YFLogxK
U2 - 10.1016/j.jtice.2025.106136
DO - 10.1016/j.jtice.2025.106136
M3 - Article
AN - SCOPUS:105002690264
SN - 1876-1070
VL - 172
JO - Journal of the Taiwan Institute of Chemical Engineers
JF - Journal of the Taiwan Institute of Chemical Engineers
M1 - 106136
ER -