TY - JOUR
T1 - Synthesis and in vitro antiprotozoal activity of 5-nitrothiophene-2-carboxaldehyde thiosemicarbazone derivatives
AU - Bharti, Neelam
AU - Husain, Kakul
AU - Gonzalez Garza, M. T.
AU - Cruz-Vega, Delia E.
AU - Castro-Garza, J.
AU - Mata-Cardenas, Benito D.
AU - Naqvi, Fehmida
AU - Azam, Amir
PY - 2002/12
Y1 - 2002/12
N2 - Several thiosemicarbazone derivatives of 5-nitrothiophene-2-carboxaldehyde were prepared by the simple process in which N4-thiosemicarbazone moiety was replaced by aliphatic, arylic and cyclic amine. Among these thiosemicarbazones compound 11 showed significant antiamoebic activity whereas compound 3 was more active antitrichomonal than the reference drug.
AB - Several thiosemicarbazone derivatives of 5-nitrothiophene-2-carboxaldehyde were prepared by the simple process in which N4-thiosemicarbazone moiety was replaced by aliphatic, arylic and cyclic amine. Among these thiosemicarbazones compound 11 showed significant antiamoebic activity whereas compound 3 was more active antitrichomonal than the reference drug.
UR - https://www.scopus.com/pages/publications/0036888378
U2 - 10.1016/S0960-894X(02)00703-5
DO - 10.1016/S0960-894X(02)00703-5
M3 - Article
C2 - 12419387
AN - SCOPUS:0036888378
SN - 0960-894X
VL - 12
SP - 3475
EP - 3478
JO - Bioorganic and Medicinal Chemistry Letters
JF - Bioorganic and Medicinal Chemistry Letters
IS - 23
ER -