Study on In Vitro Antidiabetic Potential of Whole Plant Part of Urtica parviflora Roxb.

Diabetes mellitus is a chronic metabolic illness that has a significant impact on society’s health and economy. Because the currently available treatments have so many disadvantages, it’s important to look for alternatives. Traditional treatments employ medicinal plants, which are great options. As a result, this study proposed to evaluate the phytochemical evaluation and in vitro antidiabetic potential of whole parts of the plant Urtica parviflora Roxb. It is a perennial, polygamous herbaceous plant that grows in damp and partially shaded places. The plant Urtica parviflora Roxb. belongs to the family Urticaceae. Traditionally, whole plant parts are used in the treatment of goiter, cough, allergies, alopecia, and fevers. This plant has specialized characteristics and features of stinging hairs which are a rich source of phytoconstituents majorly 5-hydroxytryptamine and histamine. The literature study shows that very few activities and research have been done on the plant. The present study was based on an investigation of its preliminary phytochemical screening and evaluation of in vitro antidiabetic potential alpha-glucosidase and alpha-amylase enzyme inhibition. Results found that various phytochemical constituents are present in the hydro-alcoholic extract in different percentages like loss on drying(11.4%), starch (0.92%), sugar (0.66%), flavonoids (0.24%), tannins (1.24%), phenolic compounds (3.10%), proanthocyanidin (2.18%), and flavonols (0.23%) respectively.