Strategic Design of a Nanocarrier System for Nutraceuticals

The emerging application of nanotechnology has been widely proven as a promising strategy in the area of medicine, including pharmaceuticals, skincare products, food, packaging, and also as a dietary supplement. With the concept of nanoparticles, the bioavailability of nutrients and dietary supplements can be improved by increasing the absorption of the supplement from the severe conditions of the gastrointestinal tract. The safety profile and the toxicity levels need to be addressed for clinical and regulatory approval. Nutraceuticals have been proved to have a positive physiological result on the human body in many research papers as well as evidence-based systems. Many research works have been put forward proving the ability of nano-nutraceuticals with an increase in bioavailability through various in vitro and in vivo models. In this chapter, we put forward the strategic link between nano-based formulations and nutraceuticals for the mitigation of various health disorders. Nanotechnology is applied for the co-delivery of various nutraceuticals from vegetables, fruits, vitamins, legumes, and spices as a therapeutic regimen. Hence, the need for nutraceuticals is increasing at the global level; on the other hand, the lipophilicity of most dietary supplements causes bioavailability problems, including biopharmaceutical considerations. In this aspect, the incorporation of nanotechnology into the nutraceuticals would provide wider scope in overcoming the issue; in addition, it would also improve the digestive and immune systems and thereby, the cognitive behavior-related aspects. The design of the nanodelivery system is likely important to provide stimulus response for the nutraceutical delivery. This chapter puts forward the strategic design of the nutraceutical delivery system for conceptual therapeutic application.