Sodium alginate based drug delivery in management of breast cancer

Mohammad Arshad Javed Shaikh; Khalid Saad Alharbi; Waleed Hassan Almalki; Syed Sarim Imam; Mohammed Albratty; Abdulkarim M. Meraya; Sami I. Alzarea; Imran Kazmi; Fahad A. Al-Abbasi; Obaid Afzal; Abdulmalik Saleh Alfawaz Altamimi; Yogendra Singh; Sachin Kumar Singh; Kamal Dua; Gaurav Gupta

doi:10.1016/j.carbpol.2022.119689

Sodium alginate based drug delivery in management of breast cancer

Mohammad Arshad Javed Shaikh, Khalid Saad Alharbi, Waleed Hassan Almalki, Syed Sarim Imam, Mohammed Albratty, Abdulkarim M. Meraya, Sami I. Alzarea, Imran Kazmi, Fahad A. Al-Abbasi, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Yogendra Singh, Sachin Kumar Singh, Kamal Dua, Gaurav Gupta

Pharmaceutical Chemistry

Research output: Contribution to journal › Review article › peer-review

102 Scopus citations

Abstract

Among women, breast cancer (B·C.) is a common form of cancer that can strike either developed or developing countries. In addition to pregnancy-related variables, hormone therapy lifestyle factors (e.g., physical inactivity, smoking, and alcohol use) may all influence the progression of B·C. The creation of anti-B·C. medication carriers with better stability, controlled and targeted administration, and the goal of minimizing unwanted effects has taken a lot of time and effort. Naturally generated biopolymers-based pharmaceutical delivery techniques have attracted attention for their potential use in treating B·C. It's been shown that natural polymers can deliver high medication concentrations to the desired place and provide prolonged release of pharmaceuticals useful in treating B.C. Alginate is one of the most commonly used drug carriers for delayed and targeted release. In present review will discuss the utilization of sodium alginate as an carrier of anticancer drug, such as paclitaxel, doxorubicin, tamoxifen, curcumin, and others.

Original language	English
Article number	119689
Journal	Carbohydrate Polymers
Volume	292
DOIs	https://doi.org/10.1016/j.carbpol.2022.119689
State	Published - 15 Sep 2022

Keywords

Breast cancer
Drug carrier
Polysaccharides
Signaling pathway
Sodium alginate

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.carbpol.2022.119689

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Shaikh, M. A. J., Alharbi, K. S., Almalki, W. H., Imam, S. S., Albratty, M., Meraya, A. M., Alzarea, S. I., Kazmi, I., Al-Abbasi, F. A., Afzal, O., Altamimi, A. S. A., Singh, Y., Singh, S. K., Dua, K., & Gupta, G. (2022). Sodium alginate based drug delivery in management of breast cancer. Carbohydrate Polymers, 292, Article 119689. https://doi.org/10.1016/j.carbpol.2022.119689

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abstract = "Among women, breast cancer (B·C.) is a common form of cancer that can strike either developed or developing countries. In addition to pregnancy-related variables, hormone therapy lifestyle factors (e.g., physical inactivity, smoking, and alcohol use) may all influence the progression of B·C. The creation of anti-B·C. medication carriers with better stability, controlled and targeted administration, and the goal of minimizing unwanted effects has taken a lot of time and effort. Naturally generated biopolymers-based pharmaceutical delivery techniques have attracted attention for their potential use in treating B·C. It's been shown that natural polymers can deliver high medication concentrations to the desired place and provide prolonged release of pharmaceuticals useful in treating B.C. Alginate is one of the most commonly used drug carriers for delayed and targeted release. In present review will discuss the utilization of sodium alginate as an carrier of anticancer drug, such as paclitaxel, doxorubicin, tamoxifen, curcumin, and others.",

keywords = "Breast cancer, Drug carrier, Polysaccharides, Signaling pathway, Sodium alginate",

author = "Shaikh, \{Mohammad Arshad Javed\} and Alharbi, \{Khalid Saad\} and Almalki, \{Waleed Hassan\} and Imam, \{Syed Sarim\} and Mohammed Albratty and Meraya, \{Abdulkarim M.\} and Alzarea, \{Sami I.\} and Imran Kazmi and Al-Abbasi, \{Fahad A.\} and Obaid Afzal and Altamimi, \{Abdulmalik Saleh Alfawaz\} and Yogendra Singh and Singh, \{Sachin Kumar\} and Kamal Dua and Gaurav Gupta",

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doi = "10.1016/j.carbpol.2022.119689",

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AU - Shaikh, Mohammad Arshad Javed

AU - Alharbi, Khalid Saad

AU - Almalki, Waleed Hassan

AU - Imam, Syed Sarim

AU - Albratty, Mohammed

AU - Meraya, Abdulkarim M.

AU - Alzarea, Sami I.

AU - Kazmi, Imran

AU - Al-Abbasi, Fahad A.

AU - Afzal, Obaid

AU - Altamimi, Abdulmalik Saleh Alfawaz

AU - Singh, Yogendra

AU - Singh, Sachin Kumar

AU - Dua, Kamal

AU - Gupta, Gaurav

PY - 2022/9/15

Y1 - 2022/9/15

N2 - Among women, breast cancer (B·C.) is a common form of cancer that can strike either developed or developing countries. In addition to pregnancy-related variables, hormone therapy lifestyle factors (e.g., physical inactivity, smoking, and alcohol use) may all influence the progression of B·C. The creation of anti-B·C. medication carriers with better stability, controlled and targeted administration, and the goal of minimizing unwanted effects has taken a lot of time and effort. Naturally generated biopolymers-based pharmaceutical delivery techniques have attracted attention for their potential use in treating B·C. It's been shown that natural polymers can deliver high medication concentrations to the desired place and provide prolonged release of pharmaceuticals useful in treating B.C. Alginate is one of the most commonly used drug carriers for delayed and targeted release. In present review will discuss the utilization of sodium alginate as an carrier of anticancer drug, such as paclitaxel, doxorubicin, tamoxifen, curcumin, and others.

AB - Among women, breast cancer (B·C.) is a common form of cancer that can strike either developed or developing countries. In addition to pregnancy-related variables, hormone therapy lifestyle factors (e.g., physical inactivity, smoking, and alcohol use) may all influence the progression of B·C. The creation of anti-B·C. medication carriers with better stability, controlled and targeted administration, and the goal of minimizing unwanted effects has taken a lot of time and effort. Naturally generated biopolymers-based pharmaceutical delivery techniques have attracted attention for their potential use in treating B·C. It's been shown that natural polymers can deliver high medication concentrations to the desired place and provide prolonged release of pharmaceuticals useful in treating B.C. Alginate is one of the most commonly used drug carriers for delayed and targeted release. In present review will discuss the utilization of sodium alginate as an carrier of anticancer drug, such as paclitaxel, doxorubicin, tamoxifen, curcumin, and others.

KW - Breast cancer

KW - Drug carrier

KW - Polysaccharides

KW - Signaling pathway

KW - Sodium alginate

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DO - 10.1016/j.carbpol.2022.119689

M3 - Review article

C2 - 35725179

AN - SCOPUS:85132266333

SN - 0144-8617

VL - 292

JO - Carbohydrate Polymers

JF - Carbohydrate Polymers

M1 - 119689

ER -

Sodium alginate based drug delivery in management of breast cancer

Abstract

Keywords

UN SDGs

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