TY - JOUR
T1 - Serum trace elements in insulin-dependent and non-insulin-dependent diabetes
T2 - A comparative study
AU - Ahmed, Ahmed M.
AU - Khabour, Omar F.
AU - Awadalla, Akram H.
AU - Waggiallah, Hisham A.
N1 - Publisher Copyright:
© 2018 Ahmed et al.
PY - 2018
Y1 - 2018
N2 - Background: Diabetes mellitus is associated with imbalance in body trace elements. The aim of the current investigation was to compare the levels of trace elements (Zn, Mg, Mn, Cu, Na, K, Fe, Ca, Cr, and Se) in insulin dependent (IDDM) and non-insulin dependent (NIDDM) diabetes. Methods: A total of 100 patients with diabetes (40 IDDM and 60 NIDDM) and 50 healthy subjects were recruited in the study from both genders. Biochemical measures include glucose, lipids, and HbA1C. Results: The results showed that Zn, Mg, Cu and Cr were significant lower in patients with diabetes compared to the control group (P<0.01). In addition, Zn and Cr were significantly lower in IDDM than NIDDM (P<0.05). Moreover, Zn and Mg levels were inversely correlated with HbA1c in IDDM and NIDDM (P<0.05). Zn was inversely correlated with fasting blood glucose in IDDM (P<0.05). Finally, no correlation between trace element levels with BMI was found (P>0.05). Conclusion: Disturbance in trace element profile among IDDM and NIDDM is similar.
AB - Background: Diabetes mellitus is associated with imbalance in body trace elements. The aim of the current investigation was to compare the levels of trace elements (Zn, Mg, Mn, Cu, Na, K, Fe, Ca, Cr, and Se) in insulin dependent (IDDM) and non-insulin dependent (NIDDM) diabetes. Methods: A total of 100 patients with diabetes (40 IDDM and 60 NIDDM) and 50 healthy subjects were recruited in the study from both genders. Biochemical measures include glucose, lipids, and HbA1C. Results: The results showed that Zn, Mg, Cu and Cr were significant lower in patients with diabetes compared to the control group (P<0.01). In addition, Zn and Cr were significantly lower in IDDM than NIDDM (P<0.05). Moreover, Zn and Mg levels were inversely correlated with HbA1c in IDDM and NIDDM (P<0.05). Zn was inversely correlated with fasting blood glucose in IDDM (P<0.05). Finally, no correlation between trace element levels with BMI was found (P>0.05). Conclusion: Disturbance in trace element profile among IDDM and NIDDM is similar.
KW - Diabetes mellitus
KW - IDDM
KW - NIDDM
KW - Trace elements
UR - http://www.scopus.com/inward/record.url?scp=85058999524&partnerID=8YFLogxK
U2 - 10.2147/DMSO.S186602
DO - 10.2147/DMSO.S186602
M3 - Article
AN - SCOPUS:85058999524
SN - 1178-7007
VL - 11
SP - 887
EP - 892
JO - Diabetes, Metabolic Syndrome and Obesity
JF - Diabetes, Metabolic Syndrome and Obesity
ER -
