Selective extraction of captafol from blood and river water samples using molecularly imprinted polymers

In this study, the captafol molecularly imprinted polymers were first prepared using the precipitation polymerization method, using captafol as the template molecule and acrylamide (Am) as the functional monomer. The synthesized polymers have spherical particles with a loose, porous surface, as determined through scanning electron microscopy. The polymer was analyzed using BET, Thermogravimetric Analysis (TGA), Scanning Electron Microscopy (SEM), and Fourier Transform Infrared Spectroscopy (FTIR). The polymers demonstrated a high adsorption efficiency of up to 90 % and specific recognition ability towards captafol, based on the results of the dynamic and static adsorption assays. The factors affecting MIPs’ binding efficiency were carefully optimized. Studies were established to analyze captafol in water and human blood serum samples under optimal conditions. Through adsorption kinetics, adsorption isotherms, and selectivity tests, this suggested approach demonstrated good MIP adsorption characteristics for captafol. The resulting Cap-MIPs showed notable selectivity for captafol as compared to folpet, high adsorption capacity (90 %), and good reusability, with the ability to reach adsorption equilibrium in less than 60 min. The results showed that the Cap-MIPs strategy exhibited high selectivity, good consistency, and high sensitivity, making it an efficient way to enrich and recognize captafol in a complex blood serum matrix.