TY - JOUR
T1 - Prevalence of human immunodeficiency virus among pulmonary tuberculosis patients
T2 - A cross-sectional study
AU - Moglad, Ehssan H.O.
AU - Ahmed, Dalia A.O.
AU - Awad AL-Kareem, Samah M.M.
AU - Elgoraish, Amanda G.
AU - Ali, Hatim T.O.
AU - Altayb, Hisham N.
N1 - Publisher Copyright:
© 2020 The Societies and John Wiley & Sons Australia, Ltd
PY - 2020/12
Y1 - 2020/12
N2 - Tuberculosis (TB) is caused by Mycobacterium tuberculosis and is an endemic disease in Sudan, where it has rapidly become the major complication of human immunodeficiency virus (HIV) infection. Thus, this study aimed to determine the prevalence of HIV among TB patients and evaluate the co-infection rate. The association of HIV prevalence with gender, age, and duration of treatment as risk factors was also determined. A descriptive cross-sectional study was performed in Omdurman Abu Anga Hospital, Khartoum, Sudan, from October 2018 to March 2019. A total of 281 blood samples were obtained randomly from pulmonary TB patients. The plasma was examined for the presence of HIV antibodies using sandwich ELISA. A structured questionnaire was used during data collection. A noticeable marker for HIV immunoglobulin M/immunoglobulin G was found in 12 patients (4.3%), of which five patients (41.7%) were diagnosed as new TB cases. Moreover, the relationship between age, sex, and duration of TB treatment and the prevalence of HIV was not significantly different (P > 0.05). In conclusion, the prevalence of HIV antibodies among TB pulmonary patients is high. Therefore, all TB patients should be examined for HIV risk factors and advised to undergo HIV testing. Further studies are essential to provide more insights into the epidemiology of the co-infection to better report the double burden of HIV and TB among TB patients in Sudan.
AB - Tuberculosis (TB) is caused by Mycobacterium tuberculosis and is an endemic disease in Sudan, where it has rapidly become the major complication of human immunodeficiency virus (HIV) infection. Thus, this study aimed to determine the prevalence of HIV among TB patients and evaluate the co-infection rate. The association of HIV prevalence with gender, age, and duration of treatment as risk factors was also determined. A descriptive cross-sectional study was performed in Omdurman Abu Anga Hospital, Khartoum, Sudan, from October 2018 to March 2019. A total of 281 blood samples were obtained randomly from pulmonary TB patients. The plasma was examined for the presence of HIV antibodies using sandwich ELISA. A structured questionnaire was used during data collection. A noticeable marker for HIV immunoglobulin M/immunoglobulin G was found in 12 patients (4.3%), of which five patients (41.7%) were diagnosed as new TB cases. Moreover, the relationship between age, sex, and duration of TB treatment and the prevalence of HIV was not significantly different (P > 0.05). In conclusion, the prevalence of HIV antibodies among TB pulmonary patients is high. Therefore, all TB patients should be examined for HIV risk factors and advised to undergo HIV testing. Further studies are essential to provide more insights into the epidemiology of the co-infection to better report the double burden of HIV and TB among TB patients in Sudan.
KW - co-infection
KW - HIV
KW - prevalence
KW - pulmonary tuberculosis
KW - Sudan
UR - http://www.scopus.com/inward/record.url?scp=85094216372&partnerID=8YFLogxK
U2 - 10.1111/1348-0421.12856
DO - 10.1111/1348-0421.12856
M3 - Article
C2 - 33090528
AN - SCOPUS:85094216372
SN - 0385-5600
VL - 64
SP - 810
EP - 814
JO - Microbiology and Immunology
JF - Microbiology and Immunology
IS - 12
ER -
