TY - JOUR
T1 - Prevalence and associated factors of fatigue among breast cancer patients in Malaysia—A prospective study
AU - Muthanna, Fares M.S.
AU - Iqbal, Muhammad Shahid
AU - Karuppannan, Mahmathi
AU - Abdulrahman, Egbal
AU - Adulyarat, Najmee
AU - Al-Ghorafi, Mokhtar Abd Hafiz Abd Alhamid
AU - Barhoum, Humam Shaaban
N1 - Publisher Copyright:
© 2022 Fares M. S. Muthanna et al. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).
PY - 2022
Y1 - 2022
N2 - The aim of this study was to determine the prevalence and factors associated with fatigue among breast cancer patients in Malaysia. This study was a prospective observational study and data were collected from medical records of Hospital Kuala Lumpur, University of Malaya Medical Center, and National Cancer Institute in the period between July 2019 and April 2020. The incidence of fatigue was determined by detecting whether or not fatigue developed during the course of chemotherapy. Severity of fatigue was determined by the Brief Fatigue Inventory scale after informed written consent was obtained. A chi-squared test was used to analyze the correlations between categorical variables, and logistic regression was used to evaluate the associations of risk factors with the presence of cancerrelated fatigue. Out of a total population of 576 breast cancer patients, 292 had met the inclusion criteria and fatigue occurred at a rate of 58.9%. Our findings indicated that age, body mass index, smoking, number of chemotherapy regimens, fluorouracil, epirubicin, and cyclophosphamide were all associated with the presence of fatigue among breast patients (p < 0.05).
AB - The aim of this study was to determine the prevalence and factors associated with fatigue among breast cancer patients in Malaysia. This study was a prospective observational study and data were collected from medical records of Hospital Kuala Lumpur, University of Malaya Medical Center, and National Cancer Institute in the period between July 2019 and April 2020. The incidence of fatigue was determined by detecting whether or not fatigue developed during the course of chemotherapy. Severity of fatigue was determined by the Brief Fatigue Inventory scale after informed written consent was obtained. A chi-squared test was used to analyze the correlations between categorical variables, and logistic regression was used to evaluate the associations of risk factors with the presence of cancerrelated fatigue. Out of a total population of 576 breast cancer patients, 292 had met the inclusion criteria and fatigue occurred at a rate of 58.9%. Our findings indicated that age, body mass index, smoking, number of chemotherapy regimens, fluorouracil, epirubicin, and cyclophosphamide were all associated with the presence of fatigue among breast patients (p < 0.05).
KW - Associated factors
KW - Breast cancer
KW - Cancer-related fatigue
KW - Prevalence
UR - http://www.scopus.com/inward/record.url?scp=85140037779&partnerID=8YFLogxK
U2 - 10.7324/JAPS.2022.121014
DO - 10.7324/JAPS.2022.121014
M3 - Article
AN - SCOPUS:85140037779
SN - 2231-3354
VL - 12
SP - 131
EP - 139
JO - Journal of Applied Pharmaceutical Science
JF - Journal of Applied Pharmaceutical Science
IS - 10
ER -
