TY - JOUR
T1 - Phytochemical Analysis, Standardization, and Antidiabetic Evaluation of Caesalpinia bonducella
AU - Alam, Prawez
AU - Alqarni, Mohammed H.
AU - Foudah, Ahmed I.
AU - Ali, Mohammed
AU - Shakeel, Faiyaz
N1 - Publisher Copyright:
© 2022, Colegio de Farmaceuticos de la Provincia de Buenos Aires. All rights reserved.
PY - 2022
Y1 - 2022
N2 - Caesalpinia bonducella (CB) Fleming (commonly known as fever nut) is a traditional ayurvedic medicinal plant, belongs to family Caesalpiniaceae. In traditional ayurvedic system of Indian medicine, it is used as an antimalarial, antihelmintic, calming, antiperiodic, antipyretic, and antimicrobial agent. As a result, the goal of this work was to perform phytochemical analysis, physicochemical standardization, and antidiabetic evaluation of CB. The samples of CB were collected from New Delhi, India. The phytochemical analysis and physicochemical standardization of CB was performed, which could help in rapid identification and selection of the active pharmaceutical components from different varieties of adulterants. The aqueous extract of CB was selected for antidiabetic evaluation in rats. The aqueous extract of CB was found to reduce the blood glucose levels in rats and hence can be used in the control and management of diabetes mellitus. These results and observations indicated the potential of CB in the treatment of diabetes mellitus.
AB - Caesalpinia bonducella (CB) Fleming (commonly known as fever nut) is a traditional ayurvedic medicinal plant, belongs to family Caesalpiniaceae. In traditional ayurvedic system of Indian medicine, it is used as an antimalarial, antihelmintic, calming, antiperiodic, antipyretic, and antimicrobial agent. As a result, the goal of this work was to perform phytochemical analysis, physicochemical standardization, and antidiabetic evaluation of CB. The samples of CB were collected from New Delhi, India. The phytochemical analysis and physicochemical standardization of CB was performed, which could help in rapid identification and selection of the active pharmaceutical components from different varieties of adulterants. The aqueous extract of CB was selected for antidiabetic evaluation in rats. The aqueous extract of CB was found to reduce the blood glucose levels in rats and hence can be used in the control and management of diabetes mellitus. These results and observations indicated the potential of CB in the treatment of diabetes mellitus.
KW - antidiabetic evaluation
KW - Caesalpinia bonducella
KW - physicochemical standardization
KW - phytochemical analysis
UR - http://www.scopus.com/inward/record.url?scp=85128704410&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85128704410
SN - 0326-2383
VL - 41
SP - 872
EP - 880
JO - Latin American Journal of Pharmacy
JF - Latin American Journal of Pharmacy
IS - 4
ER -