TY - JOUR
T1 - Optical-based biosensor for detection of oncomarker CA 125, recent progress and current status
AU - Valerievich Yumashev, Alexei
AU - Rudiansyah, Mohammad
AU - Chupradit, Supat
AU - Kadhim, Mustafa M.
AU - Turki Jalil, Abduladheem
AU - Abdelbasset, Walid Kamal
AU - Suksatan, Wanich
AU - Mireya Romero Parra, Rosario
AU - Fakri Mustafa, Yasser
AU - Abdullaev, Bekhzod
AU - Bidares, Ramtin
N1 - Publisher Copyright:
© 2022 Elsevier Inc.
PY - 2022/10/15
Y1 - 2022/10/15
N2 - Ovarian cancer (OV) is the second most mortal gynecological malignancy. The oncomarker CA125 has been used as the main ovarian cancer marker for diagnosing and screening ovarian cancer in stages I and II. Therefore, sensitive and real-time detection of CA 125 is critical in ovarian cancer monitoring. Various tests are used to diagnose the CA 125. In recent years, modern methods such as biosensor technology have replaced the old tests for rapid, sensitive and specific detection of CA 125. Various types of biosensors are being developed, among which Surface Plasmon resonance (SPR) biosensors are one of the most important and remarkable types. Considering the importance of SPR biosensors in the diagnosis of enocomarker CA 125, the main focus of the present study is to consolidate the research work from the past two decade to the present. Also, the advantages and challenges in SPR biosensors development have been considered in the detection of CA 125 oncomarker.
AB - Ovarian cancer (OV) is the second most mortal gynecological malignancy. The oncomarker CA125 has been used as the main ovarian cancer marker for diagnosing and screening ovarian cancer in stages I and II. Therefore, sensitive and real-time detection of CA 125 is critical in ovarian cancer monitoring. Various tests are used to diagnose the CA 125. In recent years, modern methods such as biosensor technology have replaced the old tests for rapid, sensitive and specific detection of CA 125. Various types of biosensors are being developed, among which Surface Plasmon resonance (SPR) biosensors are one of the most important and remarkable types. Considering the importance of SPR biosensors in the diagnosis of enocomarker CA 125, the main focus of the present study is to consolidate the research work from the past two decade to the present. Also, the advantages and challenges in SPR biosensors development have been considered in the detection of CA 125 oncomarker.
KW - Biosensors
KW - CA 125
KW - Nanomaterial
KW - Ovarian cancer (OV)
KW - SPR
UR - http://www.scopus.com/inward/record.url?scp=85136548096&partnerID=8YFLogxK
U2 - 10.1016/j.ab.2022.114750
DO - 10.1016/j.ab.2022.114750
M3 - Review article
C2 - 35643149
AN - SCOPUS:85136548096
SN - 0003-2697
VL - 655
JO - Analytical Biochemistry
JF - Analytical Biochemistry
M1 - 114750
ER -
