Novel series of dihydroquinolindihydro-spiro[indoline-3,6’-[1,3]thiazine]-5′-carbonitrile derivatives

Asmaa H. Mohamed, Mohammed B. Alshammari, Esmaat M. El-Sheref, Ashraf A. Aly

Research output: Contribution to journalArticlepeer-review

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Abstract

A series of new spiro[indoline-3,6’-[1,3]thiazines] were synthesized in modest yields by refluxing of substituted (1,2-dihydroquinolin-3-yl)-methylene)hydrazinecarbothioamides with 2-(2-oxoindolin-3-ylidene)malononitrile in pyridine as a solvent. The structure assignment of all obtained products has been confirmed by 1H, 13C NMR, 2D-NMR, 15N NMR spectroscopy in addition to elemental analyses. The possible mechanism for the reaction is also discussed.

Original languageEnglish
Article number128618
JournalJournal of Molecular Structure
Volume1219
DOIs
StatePublished - 5 Nov 2020

Keywords

  • 2-(Oxoindolinylidene)malononitrile
  • Spiro[indoline-3,6'[1,3]thiazine
  • Thiosemicarbazones

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