TY - JOUR
T1 - LncRNA PVT1
T2 - as a therapeutic target for breast cancer
AU - Baljon, Kamilya Jamel
AU - Ramaiah, Pushpamala
AU - Saleh, Ebraheem Abdu Musad
AU - Al-dolaimy, F.
AU - Al-Dami, Farqad Hassan
AU - Gandla, Kumaraswamy
AU - Alkhafaji, Adnan Taan
AU - Abbas, Ahmed hussien R.
AU - Alsaalamy, Ali Hashiem
AU - Bisht, Yashwant Singh
N1 - Publisher Copyright:
© 2023 Elsevier GmbH
PY - 2023/8
Y1 - 2023/8
N2 - A significant number of women are identified with breast cancer (BC) every year, making it among the most prevalent malignancies and one of the leading causes of mortality globally. Despite significant progress in understanding BC pathogenesis and treatment options, there is still a need to identify new therapeutic targets and develop more effective treatments. LncRNAs have been discovered as biomarkers and a promising target for various cancers, including BC. PVT1 is a particular one of these lncRNAs, and research has indicated that it has a significant impact on the appearance and progression of BC.PVT1 is an attractive therapeutic target for BC due to its role in promoting cancer cell growth, metastasis and invasion. In addition to its potential as a treatment strategy, PVT1 may also have diagnostic value in BC. In this article, we will discuss targeting PVT1 as a treatment strategy for BC.
AB - A significant number of women are identified with breast cancer (BC) every year, making it among the most prevalent malignancies and one of the leading causes of mortality globally. Despite significant progress in understanding BC pathogenesis and treatment options, there is still a need to identify new therapeutic targets and develop more effective treatments. LncRNAs have been discovered as biomarkers and a promising target for various cancers, including BC. PVT1 is a particular one of these lncRNAs, and research has indicated that it has a significant impact on the appearance and progression of BC.PVT1 is an attractive therapeutic target for BC due to its role in promoting cancer cell growth, metastasis and invasion. In addition to its potential as a treatment strategy, PVT1 may also have diagnostic value in BC. In this article, we will discuss targeting PVT1 as a treatment strategy for BC.
KW - Breast cancer
KW - Cancer cells
KW - Effective micro-RNAs
KW - LncRNA-PVT1
UR - http://www.scopus.com/inward/record.url?scp=85166156585&partnerID=8YFLogxK
U2 - 10.1016/j.prp.2023.154675
DO - 10.1016/j.prp.2023.154675
M3 - Review article
C2 - 37531833
AN - SCOPUS:85166156585
SN - 0344-0338
VL - 248
JO - Pathology Research and Practice
JF - Pathology Research and Practice
M1 - 154675
ER -
