Improvement of Medical Applicability of Hydroxyapatite/Antimonous Oxide/Graphene Oxide Mixed Systems for Biomedical Application

A. A. Menazea, Mervat S. Mostafa, Nasser S. Awwad, H. Elhosiny Ali, Moustapha Eid Moustapha, Majed A. Bajaber

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

This study supports the binary and ternary merging tactic, this methodology is useful in the creation of new features that lacked in the parent constituents. Ra develops to reach its peak of 4.25 nm upon HAP/Sb2O3/GO which is shadowed by HAP/Sb2O3 with 3.87 nm. EDX technique offers quantitative, and qualitative elemental composition of the studied composite, where C, O, P, Ca, and Sb elements records 17.14, 66, 8.7, 7.57, and0.58%, respectively. Consequently, the composition is pure. Also, The BET technique’s resultant surface area is 39.49 for HAP/Sb2O3, and 50.76 m2/g for HAP/Sb2O3/GO. Additionally, The (HAP/GO, and HAP/Sb2O3/GO) ceramic composites microhardness was 3.2 ± 0.2 GPa for binary composite, and 3.5 ± 0.3 GPa for ternary composite. Thus, GO nano-materials enhance mechanical behavior. Applicably, the merging of the three components in one ternary nanocomposite presents the highest viability with 98.4 ± 0.8%, besides the highest antibacterial performance by 15.2 ± 0.4 mm for Escherichia coli and 16.1 ± 0.5 mm for Staphylococcus aureus.

Original languageEnglish
Pages (from-to)3220-3234
Number of pages15
JournalJournal of Inorganic and Organometallic Polymers and Materials
Volume32
Issue number8
DOIs
StatePublished - Aug 2022

Keywords

  • Antibacterial
  • Cell viability
  • Graphene oxide
  • Hydroxyapatite
  • SbO

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