TY - JOUR
T1 - Impact of Psychological Distress on Clinical and Patients’ Reported Outcomes and its Associated Drug-Related Problems among Warfarin Patients
AU - Iqbal, Muhammad Zahid
AU - Alqahtani, Saad Saeed
AU - Khan, Salah Ud Din
AU - Vohra, Saeed
AU - Mohammed, Rafiuddin
AU - Mubarak, Naeem
AU - Farooqui, Sadaf
AU - Kassab, Yaman Walid
AU - Alahmari, Abdullah K.
AU - Aldosari, Saad
AU - Shafie, Yahya Mansour
AU - Huda, Arwa
AU - Salahuddin, Amra
AU - Kabli, Ragdah Talal
AU - Khan, Mohd Faiyaz
AU - Iqbal, Muhammad Shahid
N1 - Publisher Copyright:
© 2023, Colegio de Farmaceuticos de la Provincia de Buenos Aires. All rights reserved.
PY - 2023
Y1 - 2023
N2 - Psychological distress often factors into severe undesirable feelings and results in prolonged negative outcomes among patients with chronic cardiac diseases particularly when they are on warfarin. The main objective of the current study was to assess psychological distress among warfarin patients and its association to various clinical and patients’ reported outcomes and drug-related problems. A cross-sectional study using Perceived Stress Scale 10 (PSS 10) was performed among patients taking warfarin. Numerous clinical, sociodemographic and patients reported clinical data were collected. Univariate and multivariate analyses were performed to determine various factors affecting patients’ diseases state regarding psychological distress, clinical and patients’ reported outcomes and observed drug-related problems among warfarin patients diagnosed with various cardiac diseases. Descriptive and inferential statistics were applied using the Statistical Package for Social Sciences (SPSS) version 24.0. A p-value < 0.05 was considered statistically significant. There were more female patients (n = 238, 65.9%) than the male patients (n = 123, 34.1%) in total of 361 studied patients. The mean psychological distress of 14.00±6.87 was reported among the current studied cohort of warfarin patients. Multiple logistic regression revealed that a statistically significant difference (p < 0.05) was present in the age variable among the studied warfarin patients. The present study evaluated that age was a pure contributor of severe psychological distress among warfarin patients. Major drug-related problems observed were drug choice, high dose, low dose, drug usage, contraindications and miscellaneous types. Healthcare professionals can play a vital role in decreasing psychological distress among cardiac patients on warfarin.
AB - Psychological distress often factors into severe undesirable feelings and results in prolonged negative outcomes among patients with chronic cardiac diseases particularly when they are on warfarin. The main objective of the current study was to assess psychological distress among warfarin patients and its association to various clinical and patients’ reported outcomes and drug-related problems. A cross-sectional study using Perceived Stress Scale 10 (PSS 10) was performed among patients taking warfarin. Numerous clinical, sociodemographic and patients reported clinical data were collected. Univariate and multivariate analyses were performed to determine various factors affecting patients’ diseases state regarding psychological distress, clinical and patients’ reported outcomes and observed drug-related problems among warfarin patients diagnosed with various cardiac diseases. Descriptive and inferential statistics were applied using the Statistical Package for Social Sciences (SPSS) version 24.0. A p-value < 0.05 was considered statistically significant. There were more female patients (n = 238, 65.9%) than the male patients (n = 123, 34.1%) in total of 361 studied patients. The mean psychological distress of 14.00±6.87 was reported among the current studied cohort of warfarin patients. Multiple logistic regression revealed that a statistically significant difference (p < 0.05) was present in the age variable among the studied warfarin patients. The present study evaluated that age was a pure contributor of severe psychological distress among warfarin patients. Major drug-related problems observed were drug choice, high dose, low dose, drug usage, contraindications and miscellaneous types. Healthcare professionals can play a vital role in decreasing psychological distress among cardiac patients on warfarin.
KW - cardiac patients
KW - chronic
KW - PSS 10
KW - psychological distress
KW - warfarin
UR - http://www.scopus.com/inward/record.url?scp=85161370633&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85161370633
SN - 0326-2383
VL - 42
SP - 554
EP - 561
JO - Latin American Journal of Pharmacy
JF - Latin American Journal of Pharmacy
IS - 3
ER -