Highly responsive antibacterial behaviour of ultrafine, crystalline 10B-enriched hexagonal boron nitride nanoparticles against Actinomycete and Klebsiella pneumonia

Pervaiz Fazale Ahmad, Abdul Manan, Awais Khalid Khalid , Satam Alotibi, Abdulhameed Khan, Ashir Mehmood Awan, Mayeen Uddin Khandaker

Research output: Contribution to journalArticlepeer-review

Abstract

The antibacterial properties of ultrafine, highly crystalline 10B-enriched hexagonal boron nitride nanoparticles (10BNNPs: synthesized at 1400 °C within a growth duration of 150 min) against the gram-positive bacterium (Actinomycete, and Streptococcus pyogenes), and the gram-negative bacterium (Klebsiella pneumonia, and Enterobacter) are the main focus of the current investigation. 10BNNPs are found more responsive against Actinomycete and Klebsiella pneumonia, and exhibit the largest zone of inhibition at all tested concentrations. On a concentration of 100 μg/ml particles, it has been observed that 10BNNPs provide a maximum zone of inhibition of 30 mm, and 25 mm for Actinomycete, and Klebsiella pneumonia, and a minimum zone of inhibition of 16 mm, and 14 mm for Streptococcus pyogenes, and Enterobacter, respectively. The results suggest that the synthesized 10BNNPs can be a potential alternative to the existing antibiotics against Actinomycete and Klebsiella pneumonia bacteria in the future.

Original languageEnglish
Article number131290
JournalMaterials Chemistry and Physics
Volume345
DOIs
StatePublished - 1 Nov 2025

Keywords

  • B-enriched
  • Actinomycete
  • Antibacterial
  • Klebsiella-pneumonia
  • Nanoparticles

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