TY - JOUR
T1 - High-intensity focused ultrasound (HIFU) in uterine fibroid treatment
T2 - Review study
AU - Zuhair Alhassen, Mustafa
AU - Alkhorayef, Mohammed
AU - Alzimami, Khalid S.
AU - Aljuhani, Manal Saud
AU - Adam Sulieman, Abdelmoneim
N1 - Publisher Copyright:
© Pol J Radiol 2014.
PY - 2014/10/30
Y1 - 2014/10/30
N2 - Background: High-intensity focused ultrasound (HIFU) is a highly precise medical procedure used locally to heatand destroy diseased tissue through ablation. This study intended to review HIFU in uterine fibroid therapy, to evaluate the role of HIFU in the therapy of leiomyomas as well as to review the actualclinical activities in this field including efficacy and safety measures beside the published clinicalliterature.Material/Methods: An inclusive literature review was carried out in order to review the scientific foundation, and how it resulted in the development of extracorporeal distinct devices. Studies addressing HIFU in leiomyomas were identified from a search of the Internet scientific databases. The analysis of literature was limited to journal articles written in English and published between 2000 and 2013.Results: In current gynecologic oncology, HIFU is used clinically in the treatment of leiomyomas. Clinical research on HIFU therapy for leiomyomas began in the 1990s, and the majority of patients with leiomyomas were treated predominantly with HIFUNIT 9000 and prototype single focus ultrasound devices. HIFU is a non-invasive and highly effective standard treatment with a large indication range for all sizes of leiomyomas, associated with high efficacy, low operative morbidity and no systemic side effects.Conclusions: Uterine fibroid treatment using HIFU was effective and safe in treating symptomatic uterine fibroids. Few studies are available in the literature regarding uterine artery embolization (UAE). HIFU provides an excellent option to treat uterine fibroids.
AB - Background: High-intensity focused ultrasound (HIFU) is a highly precise medical procedure used locally to heatand destroy diseased tissue through ablation. This study intended to review HIFU in uterine fibroid therapy, to evaluate the role of HIFU in the therapy of leiomyomas as well as to review the actualclinical activities in this field including efficacy and safety measures beside the published clinicalliterature.Material/Methods: An inclusive literature review was carried out in order to review the scientific foundation, and how it resulted in the development of extracorporeal distinct devices. Studies addressing HIFU in leiomyomas were identified from a search of the Internet scientific databases. The analysis of literature was limited to journal articles written in English and published between 2000 and 2013.Results: In current gynecologic oncology, HIFU is used clinically in the treatment of leiomyomas. Clinical research on HIFU therapy for leiomyomas began in the 1990s, and the majority of patients with leiomyomas were treated predominantly with HIFUNIT 9000 and prototype single focus ultrasound devices. HIFU is a non-invasive and highly effective standard treatment with a large indication range for all sizes of leiomyomas, associated with high efficacy, low operative morbidity and no systemic side effects.Conclusions: Uterine fibroid treatment using HIFU was effective and safe in treating symptomatic uterine fibroids. Few studies are available in the literature regarding uterine artery embolization (UAE). HIFU provides an excellent option to treat uterine fibroids.
KW - High-intensity focused ultrasound ablation
KW - Leiomyoma
KW - Uterine artery embolization
UR - http://www.scopus.com/inward/record.url?scp=84925164287&partnerID=8YFLogxK
U2 - 10.12659/PJR.891110
DO - 10.12659/PJR.891110
M3 - Article
AN - SCOPUS:84925164287
SN - 1733-134X
VL - 79
SP - 384
EP - 390
JO - Polish Journal of Radiology
JF - Polish Journal of Radiology
IS - 1
ER -
