TY - JOUR
T1 - Harnessing the potential of nanoprisms for diagnostic and therapeutic applications
AU - Joshi, Radhika
AU - Sharma, Swapnil
AU - Ali, Nemat
AU - Muteeb, Ghazala
AU - Fareed, Mohammad
AU - Alam, Prawez
AU - Kapoor, Devesh U.
AU - Prajapati, Bhupendra G.
N1 - Publisher Copyright:
© 2025 The Authors
PY - 2025/3
Y1 - 2025/3
N2 - Nanoprisms, a distinctive class of nanostructures, have garnered significant attention in nanomedicine due to their exceptional optical, electronic, and physicochemical properties. This review highlights the diagnostic and therapeutic potential of nanoprisms, emphasizing their transformative role in modern healthcare. First, it provides an overview of current diagnostic and therapeutic strategies within nanomedicine and underscores the unique attributes of nanoprisms. The synthesis and functionalization of nanoprisms, including seed-mediated growth and surface modification techniques like PEGylation and ligand conjugation, are discussed, showcasing how size, shape, and material composition influence their applications. Their diagnostic capabilities span bioimaging techniques, such as plasmonic and photoacoustic imaging, molecular diagnostics, and pathogen detection. In therapeutics, nanoprisms excel in photothermal cancer therapy, targeted drug delivery, and antimicrobial applications, including combating multidrug-resistant strains. Finally, the review addresses existing challenges and future opportunities in advancing nanoprism-based technologies, paving the way for innovative solutions in diagnostics and therapy.
AB - Nanoprisms, a distinctive class of nanostructures, have garnered significant attention in nanomedicine due to their exceptional optical, electronic, and physicochemical properties. This review highlights the diagnostic and therapeutic potential of nanoprisms, emphasizing their transformative role in modern healthcare. First, it provides an overview of current diagnostic and therapeutic strategies within nanomedicine and underscores the unique attributes of nanoprisms. The synthesis and functionalization of nanoprisms, including seed-mediated growth and surface modification techniques like PEGylation and ligand conjugation, are discussed, showcasing how size, shape, and material composition influence their applications. Their diagnostic capabilities span bioimaging techniques, such as plasmonic and photoacoustic imaging, molecular diagnostics, and pathogen detection. In therapeutics, nanoprisms excel in photothermal cancer therapy, targeted drug delivery, and antimicrobial applications, including combating multidrug-resistant strains. Finally, the review addresses existing challenges and future opportunities in advancing nanoprism-based technologies, paving the way for innovative solutions in diagnostics and therapy.
KW - Antibacterial
KW - Bioimaging
KW - Cancer
KW - Nanoprism
KW - Photothermal therapy
UR - http://www.scopus.com/inward/record.url?scp=85219024607&partnerID=8YFLogxK
U2 - 10.1016/j.colcom.2025.100826
DO - 10.1016/j.colcom.2025.100826
M3 - Review article
AN - SCOPUS:85219024607
SN - 2215-0382
VL - 65
JO - Colloids and Interface Science Communications
JF - Colloids and Interface Science Communications
M1 - 100826
ER -
