Abstract
Aqueous, methanol and chloroform extracts of 25 medicinal plants used in folklore medicine in Sudan were screened for in vitro activity against some Gram-positive and Gram-negative pathogenic bacteria using the cupplate agar diffusion method as an experimental models. The extracts at concentration of 0.1ml/cup showed varying degrees of inhibitory activity against the tested organisms. Extracts from Withania somnifera showed the highest activity, followed by Datura stramonium, while Zygophyllum portulacoides demonstrated the least activity when compared to 40μg/ml Ampicillin control antibiotic. The bacteria tested differed significantly in their susceptibility to plant extracts, with complete inhibition in case of Staphylococcus aureus and Bacillus subtilis. The plants which exhibited a marked antibacterial activity were shown to be rich in alkaloids, tannins and flafonoids. These results support the traditional use of these plants in the treatment of some bacterial infections in the country.
| Original language | English |
|---|---|
| Pages (from-to) | 253-256 |
| Number of pages | 4 |
| Journal | Journal of Applied Sciences Research |
| Volume | 7 |
| Issue number | 3 |
| State | Published - Mar 2011 |
| Externally published | Yes |
Keywords
- Antibacterial activity
- Folkloric medicine
- Medicinal plants
- Sudan