TY - JOUR
T1 - Evaluation of radiation exposure for patients undergoing computed tomography perfusion procedure for acute ischemic stroke
AU - Alomary, Abdullah
AU - Adam Sulieman, Abdelmoneim
AU - Alsufayan, Mohammed
AU - Alabdurazaq, Fahad
AU - Faisal, Nada
AU - Qari, Ameera
AU - Alanazi, Bandar M.
AU - Alsaadi, Mohammed
AU - Tamam, Nissren
AU - Alkhybari, Essam
AU - Bradley, David A.
N1 - Publisher Copyright:
© 2022 Elsevier Ltd
PY - 2022/11
Y1 - 2022/11
N2 - Computed tomography perfusion (CTP) is contrast-enhanced dynamic imaging of the brain utilized to assess the blood flow volume and transmit time to the brain's parenchyma. Stroke is the world's second greatest cause of mortality, accounting for 11% of all deaths, and a major cause of disability. Previous studies reported a high radiation dose per procedure with an eye lens equivalent dose (mGy) ranging from 81.0 mGy to 348.0 mGy. This study's objective is to evaluate patients exposure during CTP procedures. Materials and methods. Three hundred twenty patients with ischemic stroke underwent CTP were examined at King Fahad Medical City (KFMC). The imaging protocol consists of plain CT, CT angiography (CTA), CTP, Angiography. The volume CT Dose Index (CTDIvol, mGy) and dose length product (DLP, mGy.cm) were registered from the PACS system. The effective dose calculation (E, mSv) was extrapolated using computer software. For the CTP procedure, the mean and range of DLP (mGy.cm) for the complete procedure, CT brain, CTA, CTA digital subtraction angiography (DSA), and CTP were 1045 (105–3072), 843 (277–1530), 470.5 (210–1356), 238.8 (105–439), 2712(2012–3072) examinations, respectively. The mean and range of the effective dose (mSv) and CTDIvol (mGy) were 13.2 (10.6–17.1), 80.5 (6.11–256), in that order. The patients' doses showed wide variation due to the selection of multiple phases of acquisition and exposure factors. The dose is higher than most previous studies. Radiation dose optimization is recommended by establishing diagnostic reference level (DRL), proper CT machine setting, and increasing operators' awareness regarding radiation risks.
AB - Computed tomography perfusion (CTP) is contrast-enhanced dynamic imaging of the brain utilized to assess the blood flow volume and transmit time to the brain's parenchyma. Stroke is the world's second greatest cause of mortality, accounting for 11% of all deaths, and a major cause of disability. Previous studies reported a high radiation dose per procedure with an eye lens equivalent dose (mGy) ranging from 81.0 mGy to 348.0 mGy. This study's objective is to evaluate patients exposure during CTP procedures. Materials and methods. Three hundred twenty patients with ischemic stroke underwent CTP were examined at King Fahad Medical City (KFMC). The imaging protocol consists of plain CT, CT angiography (CTA), CTP, Angiography. The volume CT Dose Index (CTDIvol, mGy) and dose length product (DLP, mGy.cm) were registered from the PACS system. The effective dose calculation (E, mSv) was extrapolated using computer software. For the CTP procedure, the mean and range of DLP (mGy.cm) for the complete procedure, CT brain, CTA, CTA digital subtraction angiography (DSA), and CTP were 1045 (105–3072), 843 (277–1530), 470.5 (210–1356), 238.8 (105–439), 2712(2012–3072) examinations, respectively. The mean and range of the effective dose (mSv) and CTDIvol (mGy) were 13.2 (10.6–17.1), 80.5 (6.11–256), in that order. The patients' doses showed wide variation due to the selection of multiple phases of acquisition and exposure factors. The dose is higher than most previous studies. Radiation dose optimization is recommended by establishing diagnostic reference level (DRL), proper CT machine setting, and increasing operators' awareness regarding radiation risks.
KW - CT perfusion
KW - Radiation dosimetry
KW - Radiology
KW - Tissue reaction
KW - Vascular imaging
UR - http://www.scopus.com/inward/record.url?scp=85135704887&partnerID=8YFLogxK
U2 - 10.1016/j.radphyschem.2022.110447
DO - 10.1016/j.radphyschem.2022.110447
M3 - Article
AN - SCOPUS:85135704887
SN - 0969-806X
VL - 201
JO - Radiation Physics and Chemistry
JF - Radiation Physics and Chemistry
M1 - 110447
ER -
