Epigenetic regulation of stress

Mariam K. Alamoudi, Noura N. Alibrahim, Abdulmonem A. Alsaleh, Muhammad Liaquat Raza

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

Stress can have powerful and lasting effects on our bodies and behavior, partly because it changes how our genes work. These processes, such as DNA methylation, histones modifications, and non-coding RNAs, help decide when genes are active or inactive in cells experiencing stress. This can lead to lasting changes in how the cells function. It's important to understand how these changes in our genes affect our response to stress, as they can lead to problems like anxiety, depression, and heart disease. This chapter explores the link between stress and epigenetics. It talks about how our surroundings and lifestyle can impact these processes. It also shows that epigenetic treatments might help with issues created by stress. By looking at how stress affects our genes, we can discover new ways to treat stress and make medicine better for individuals, helping to lessen the bad impact of stress on our health.

Original languageEnglish
Title of host publicationStress and the Brain
Subtitle of host publicationEvidence from Molecular Mechanisms to Interventions and Therapies
PublisherElsevier B.V.
Pages205-238
Number of pages34
ISBN (Print)9780443344251
DOIs
StatePublished - Jan 2025

Publication series

NameProgress in Brain Research
Volume291
ISSN (Print)0079-6123
ISSN (Electronic)1875-7855

Keywords

  • DNA methylation
  • Epigenetics
  • Histone modifications
  • Non-coding RNAs
  • Stress

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