TY - JOUR
T1 - Effect of spatial attention on human sensorimotor integration studied by transcranial magnetic stimulation
AU - Kotb, Mamdouh Ali
AU - Mima, Tatsuya
AU - Ueki, Yoshino
AU - Begum, Tahamina
AU - Khafagi, Amal Tawfik
AU - Fukuyama, Hidenao
AU - Nagamine, Takashi
PY - 2005/5
Y1 - 2005/5
N2 - Objective: Recent transcranial magnetic stimulation (TMS) studies showed that the sensory input can decrease the motor cortex excitability (afferent inhibition). To clarify the effect of attention on sensorimotor integration, we investigated the effect of spatial attention on afferent inhibition. Methods: Right median nerve electrical stimulation followed, at variable delays (10-300 ms), by TMS over the left motor cortex was applied to 9 subjects, during 3 conditions; spatial attention to the right and left hand, and control (no attention) tasks. Results: Inhibition of the motor evoked potential occurred at inter-stimulus interval of 20 and 100 ms, which was more was marked during spatial attention to the right than to the left hand. Conclusions: Enhancement of the afferent inhibition induced by spatial attention to the stimulated side is likely to reflect the interaction between attention and sensorimotor integration. Significance: The spatial attention may modulate the sensorimotor integration studied by afferent inhibition of the MEP.
AB - Objective: Recent transcranial magnetic stimulation (TMS) studies showed that the sensory input can decrease the motor cortex excitability (afferent inhibition). To clarify the effect of attention on sensorimotor integration, we investigated the effect of spatial attention on afferent inhibition. Methods: Right median nerve electrical stimulation followed, at variable delays (10-300 ms), by TMS over the left motor cortex was applied to 9 subjects, during 3 conditions; spatial attention to the right and left hand, and control (no attention) tasks. Results: Inhibition of the motor evoked potential occurred at inter-stimulus interval of 20 and 100 ms, which was more was marked during spatial attention to the right than to the left hand. Conclusions: Enhancement of the afferent inhibition induced by spatial attention to the stimulated side is likely to reflect the interaction between attention and sensorimotor integration. Significance: The spatial attention may modulate the sensorimotor integration studied by afferent inhibition of the MEP.
KW - Afferent inhibition
KW - Sensorimotor integration
KW - Spatial attention
KW - Transcranial magnetic stimulation
UR - http://www.scopus.com/inward/record.url?scp=17144379368&partnerID=8YFLogxK
U2 - 10.1016/j.clinph.2004.12.006
DO - 10.1016/j.clinph.2004.12.006
M3 - Article
C2 - 15826862
AN - SCOPUS:17144379368
SN - 1388-2457
VL - 116
SP - 1195
EP - 1200
JO - Clinical Neurophysiology
JF - Clinical Neurophysiology
IS - 5
ER -