Effect of prophylactic treatment on visual evoked potentials (P100) in migraineurs

Mamdouh Ali Kotb, Nermin Aly Hamdy, Sayed Sobhy

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Migraine is a common neurovascular disorder. Visual evoked potential (VEP) changes, between migraineurs and normal subjects, were often conflicting.

Objective: Compare VEP (P100) in patients with migraine with and without aura to normal subjects, and the effect of prophylactic treatment.

Methods: Visual evoked potential was recorded in 32 patients with migraine and 15 healthy control subjects.

Results: P100 amplitude was significantly higher and its latency was significantly longer in patients with migraine compared to control subjects, this difference disappeared in patients with regular prophylactic treatment.

Conclusion: Cortical excitability changes may be related to the pathophysiology of migraine and the efficacy of prophylactic treatment.

Original languageEnglish
Pages (from-to)321-326
Number of pages6
JournalEgyptian Journal of Neurology, Psychiatry and Neurosurgery
Volume51
Issue number3
StatePublished - 1 Jul 2014
Externally publishedYes

Keywords

  • Migraine
  • P100
  • Visual evoked potential

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