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Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders

  • Saurabh Bhatia
  • , Rashita Makkar
  • , Tapan Behl
  • , Aayush Sehgal
  • , Sukhbir Singh
  • , Mahesh Rachamalla
  • , Vasudevan Mani
  • , Muhammad Shahid Iqbal
  • , Simona Gabriela Bungau
  • University of Nizwa
  • University of Petroleum and Energy Studies
  • Chitkara University
  • University of Saskatchewan
  • Qassim University
  • University of Oradea

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations

Abstract

Marine drugs are abundant in number, comprise of a diverse range of structures with corresponding mechanisms of action, and hold promise for the discovery of new and better treatment approaches for the management of several chronic diseases. There are huge reserves of natural marine biological compounds, as 70 percent of the Earth is covered with oceans, indicating a diversity of chemical entities on the planet. The marine ecosystems are a rich source of bioactive products and have been explored for lead drug molecules that have proven to be novel therapeutic targets. Over the last 70 years, many structurally diverse drug products and their secondary metabolites have been isolated from marine sources. The drugs obtained from marine sources have displayed an exceptional potential in the management of a wide array of diseases, ranging from acute to chronic conditions. A beneficial role of marine drugs in human health has been recently proposed. The current review highlights various marine drugs and their compounds and role in the management of chronic diseases such as cancer, diabetes, neurodegenerative diseases, and cardiovascular disorders, which has led to the development of new drug treatment approaches.

Original languageEnglish
Article number1539
JournalMolecules
Volume27
Issue number5
DOIs
StatePublished - 1 Mar 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Cancer
  • Cardiovascular disorders
  • Diabetes mellitus
  • Marine drugs
  • Neurodegeneration

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