Biosynthesis, characterization and anti-microbial activity of silver nanoparticle based gel hand wash

Mohammed Muqtader Ahmed; Farhat Fatima; Md Khalid Anwer; Saad M. Alshahrani; Ahmed Alalaiwe; Prakash Katakam

doi:10.1515/gps-2019-0027

Biosynthesis, characterization and anti-microbial activity of silver nanoparticle based gel hand wash

Pharmaceutics

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

In the current study, silver nanoparticles (AgNPs) were biosynthesised by microwave irradiation using Azadirachta indica. The formation of AgNPs was confirmed by surface plasmon resonance (SPR) band at 408 nm at UV-visible spectroscopy due to reduction of silver metal into (AgNPs) and further confirmed its particles in nano range. Nine different smart-gel hand wash were prepared by dispersing (AgNPs) in the HPMC and/or Pluronic F-127 polymers. The prepared smart gel hand wash was optimized based on pH, viscosity, spreadability, foamability, clarity. The optimized hand wash (NH5) had pH (6.6 ± 0.33), viscosity (66 ± 0.77, cp), spreadability (24.34 g-cm/s), foamability (100 mL). The optimized hand wash (NH5) showed a superior efficacy against pathogenic organisms in comparison to germ protection based marketed hand wash.

Original language	English
Pages (from-to)	577-583
Number of pages	7
Journal	Green Processing and Synthesis
Volume	8
Issue number	1
DOIs	https://doi.org/10.1515/gps-2019-0027
State	Published - 28 Jan 2019

Keywords

anti-microbial efficacy
silver nanoparticles
smart-gel hand wash
stability

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title = "Biosynthesis, characterization and anti-microbial activity of silver nanoparticle based gel hand wash",

abstract = "In the current study, silver nanoparticles (AgNPs) were biosynthesised by microwave irradiation using Azadirachta indica. The formation of AgNPs was confirmed by surface plasmon resonance (SPR) band at 408 nm at UV-visible spectroscopy due to reduction of silver metal into (AgNPs) and further confirmed its particles in nano range. Nine different smart-gel hand wash were prepared by dispersing (AgNPs) in the HPMC and/or Pluronic F-127 polymers. The prepared smart gel hand wash was optimized based on pH, viscosity, spreadability, foamability, clarity. The optimized hand wash (NH5) had pH (6.6 ± 0.33), viscosity (66 ± 0.77, cp), spreadability (24.34 g-cm/s), foamability (100 mL). The optimized hand wash (NH5) showed a superior efficacy against pathogenic organisms in comparison to germ protection based marketed hand wash.",

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author = "Ahmed, \{Mohammed Muqtader\} and Farhat Fatima and Anwer, \{Md Khalid\} and Alshahrani, \{Saad M.\} and Ahmed Alalaiwe and Prakash Katakam",

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doi = "10.1515/gps-2019-0027",

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T1 - Biosynthesis, characterization and anti-microbial activity of silver nanoparticle based gel hand wash

AU - Ahmed, Mohammed Muqtader

AU - Fatima, Farhat

AU - Anwer, Md Khalid

AU - Alshahrani, Saad M.

AU - Alalaiwe, Ahmed

AU - Katakam, Prakash

PY - 2019/1/28

Y1 - 2019/1/28

N2 - In the current study, silver nanoparticles (AgNPs) were biosynthesised by microwave irradiation using Azadirachta indica. The formation of AgNPs was confirmed by surface plasmon resonance (SPR) band at 408 nm at UV-visible spectroscopy due to reduction of silver metal into (AgNPs) and further confirmed its particles in nano range. Nine different smart-gel hand wash were prepared by dispersing (AgNPs) in the HPMC and/or Pluronic F-127 polymers. The prepared smart gel hand wash was optimized based on pH, viscosity, spreadability, foamability, clarity. The optimized hand wash (NH5) had pH (6.6 ± 0.33), viscosity (66 ± 0.77, cp), spreadability (24.34 g-cm/s), foamability (100 mL). The optimized hand wash (NH5) showed a superior efficacy against pathogenic organisms in comparison to germ protection based marketed hand wash.

AB - In the current study, silver nanoparticles (AgNPs) were biosynthesised by microwave irradiation using Azadirachta indica. The formation of AgNPs was confirmed by surface plasmon resonance (SPR) band at 408 nm at UV-visible spectroscopy due to reduction of silver metal into (AgNPs) and further confirmed its particles in nano range. Nine different smart-gel hand wash were prepared by dispersing (AgNPs) in the HPMC and/or Pluronic F-127 polymers. The prepared smart gel hand wash was optimized based on pH, viscosity, spreadability, foamability, clarity. The optimized hand wash (NH5) had pH (6.6 ± 0.33), viscosity (66 ± 0.77, cp), spreadability (24.34 g-cm/s), foamability (100 mL). The optimized hand wash (NH5) showed a superior efficacy against pathogenic organisms in comparison to germ protection based marketed hand wash.

KW - anti-microbial efficacy

KW - silver nanoparticles

KW - smart-gel hand wash

KW - stability

UR - https://www.scopus.com/pages/publications/85067630152

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DO - 10.1515/gps-2019-0027

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SN - 2191-9542

VL - 8

SP - 577

EP - 583

JO - Green Processing and Synthesis

JF - Green Processing and Synthesis

IS - 1

ER -

Biosynthesis, characterization and anti-microbial activity of silver nanoparticle based gel hand wash

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Keywords

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