TY - JOUR
T1 - Association of diabetes, fasting glucose, and the risk of glaucoma
T2 - a systematic review and meta-analysis
AU - Aldarrab, Abdulrahman
AU - Al Jarallah, Othman Jarallah
AU - Al Balawi, Hani Basher
N1 - Publisher Copyright:
© 2023 Verduci Editore s.r.l. All rights reserved.
PY - 2023
Y1 - 2023
N2 - OBJECTIVE: We designed this systematic review to summarize the diabetes-related glaucoma articles produced from 2011 to 2022. We further aimed to perform a meta-analysis to determine the vital association between these two parameters. MATERIALS AND METHODS: Data sources like PubMed, MEDLINE, and EMBASE were used to find the relevant research. Reviews, case reports, and editorial letters were excluded. Articles inspection was conducted by the main author who extracted the study title and abstract in the first screening by using keywords to find the eligible articles. Heterogeneity was accessed by using the Cochrane Q test and I2 test. RESULTS: 10 studies were reported with 2,702,136 cases of diabetes. Out of these, 64,998 incidents of glaucoma were observed. The pooled prevalence of diabetic retinopathy was 11.7% associated with glaucoma. A significant I2 value was achieved (100%) with Cochran’s Q of 183.6. CONCLUSIONS: In conclusion, we found diabetes duration, elevated IOP, and fasting glucose levels are one of the leading risk factors for glaucoma. Fasting glucose levels and diabetes are also major contributors to elevated IOP levels.
AB - OBJECTIVE: We designed this systematic review to summarize the diabetes-related glaucoma articles produced from 2011 to 2022. We further aimed to perform a meta-analysis to determine the vital association between these two parameters. MATERIALS AND METHODS: Data sources like PubMed, MEDLINE, and EMBASE were used to find the relevant research. Reviews, case reports, and editorial letters were excluded. Articles inspection was conducted by the main author who extracted the study title and abstract in the first screening by using keywords to find the eligible articles. Heterogeneity was accessed by using the Cochrane Q test and I2 test. RESULTS: 10 studies were reported with 2,702,136 cases of diabetes. Out of these, 64,998 incidents of glaucoma were observed. The pooled prevalence of diabetic retinopathy was 11.7% associated with glaucoma. A significant I2 value was achieved (100%) with Cochran’s Q of 183.6. CONCLUSIONS: In conclusion, we found diabetes duration, elevated IOP, and fasting glucose levels are one of the leading risk factors for glaucoma. Fasting glucose levels and diabetes are also major contributors to elevated IOP levels.
KW - Diabetes
KW - Fasting glucose
KW - Glaucoma
KW - Systematic review and Meta-analysis
UR - http://www.scopus.com/inward/record.url?scp=85151688513&partnerID=8YFLogxK
U2 - 10.26355/eurrev_202303_31776
DO - 10.26355/eurrev_202303_31776
M3 - Article
C2 - 37013760
AN - SCOPUS:85151688513
SN - 1128-3602
VL - 27
SP - 2419
EP - 2427
JO - European Review for Medical and Pharmacological Sciences
JF - European Review for Medical and Pharmacological Sciences
IS - 6
ER -
