Antimicrobial Resistance Pattern in a Tertiary Hospital in Al-kharj, Saudi Arabia

Antimicrobial resistance has emerged as a serious global public health concern that, by 2050, could result in up to ten million annual fatalities. This was a retrospective study that was conducted to assess the prevalence of antibiotic resistance in a tertiary hospital in Al-Kharj. A total of 601 bacterial isolates were collected in the hospital in 2020. Most of the isolates were for gram-negative bacteria (85.02%). The most prevalent bacteria were Klebsiella pneumoniae (25.46%), Escherichia coli (18.97%), Acinetobacter baumannii (16.30%), Pseudomonas aeruginosa (15.14%), and Proteus mirabilis (7.32%). The present study found high rates of antibiotic resistance among Escherichia coli, methicillin-resistant Staphylococcus aureus, Proteus mi-rabilis, Klebsiella pneumoniae, and Acinetobacter baumannii. The benefits of certain measures designed to lower these infections, along with an understanding of the clinical and financial effects of antibiotic-resistant bacterial infections, will enable better control and increased patient safety.