Antibiotic Resistance Trends among Gram Positive and Gram Negative in a Military Hospital, 2018-2021

Antimicrobial resistance has a direct influence on healthcare, causing numerous fatalities around the world, but it also has a negative impact on quality of life, resulting in significant direct and indirect expenses. The present study aimed to describe the antibiotic resistance rates among gram-positive and gram-negative bacteria during the period between 2018 and 2021 in a military hospital in Riyadh province. The study included antibiotic susceptibility test results from clinical specimens collected during the study period. A total of 1038 bacterial isolates were collected during the study period. The most isolated bacteria were Escherichia coli (31.79%), Staphylococcus aureus (26.01%), Klebsiella pneumoniae (13.10%), and Pseudomonas aeruginosa (13.00%). The present study showed that the bacterial resistance rate of the common bacteria to numerous antibiotics increased noticeably. It is critical to improve microbiological diagnoses and limit the spread of antibiotic-resistant strains, as this obstructs the most effective treatment of bacterial illnesses and narrows the therapeutic alternatives available.