TY - JOUR
T1 - Advancements in Biomaterials for Stem Cell Differentiation
AU - Shao, Mingchen
AU - Rahmdel, Mohamad
AU - Shayan, Sepideh Karkon
AU - Hassannia, Elham
AU - khedmatgozar, Mohammad
AU - Yousefi, Khadije
AU - Ali-khiavi, Payam
AU - Hjazi, Ahmed
AU - Al-Aouadi, Raed Fanoukh Aboqader
AU - Sarvestani, Paria Arjmandi
AU - Fard, Mohammad Reza Ghasemzadeh
AU - Nourizadeh, Mehrdad
AU - Khiabani, Saeid Shabestari
AU - Suliman, Muath
AU - Nataj, Paria Ganji
AU - hamzehzadeh, Sina
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025.
PY - 2025/6
Y1 - 2025/6
N2 - The field of regenerative medicine has witnessed significant advancements in recent years, particularly in the application of biomaterials to enhance stem cell differentiation. Biomaterials serve as scaffolds that can support cellular functions and influence the fate of stem cells through biochemical and physical cues. This paper reviews recent advancements in biomaterials designed for stem cell differentiation, focusing on their composition, properties, and applications in tissue engineering. We explore various types of biomaterials, including natural polymers, synthetic polymers, hydrogels, and nanomaterials, and discuss how they can be tailored to create microenvironments that promote specific differentiation pathways. Additionally, we highlight the challenges and future directions in this rapidly evolving field.
AB - The field of regenerative medicine has witnessed significant advancements in recent years, particularly in the application of biomaterials to enhance stem cell differentiation. Biomaterials serve as scaffolds that can support cellular functions and influence the fate of stem cells through biochemical and physical cues. This paper reviews recent advancements in biomaterials designed for stem cell differentiation, focusing on their composition, properties, and applications in tissue engineering. We explore various types of biomaterials, including natural polymers, synthetic polymers, hydrogels, and nanomaterials, and discuss how they can be tailored to create microenvironments that promote specific differentiation pathways. Additionally, we highlight the challenges and future directions in this rapidly evolving field.
KW - 3D bioprinting
KW - Biomaterials
KW - Extracellular matrix
KW - Hydrogels
KW - Regenerative medicine
KW - Stem cell differentiation
UR - http://www.scopus.com/inward/record.url?scp=105003412130&partnerID=8YFLogxK
U2 - 10.1007/s12015-025-10879-8
DO - 10.1007/s12015-025-10879-8
M3 - Article
C2 - 40257542
AN - SCOPUS:105003412130
SN - 2629-3269
VL - 21
SP - 1299
EP - 1310
JO - Stem Cell Reviews and Reports
JF - Stem Cell Reviews and Reports
IS - 5
ER -