Novel QuinazolinoneBased Carbonic Anhydrase IX Inhibitors (CAI IX) as Potential Antitumor Agents

Pharmacology, Toxicology and Pharmaceutical Science

1. Antitumor Activity 5%
2. Base 15%
3. Buffer 10%
4. Cancer Incidence 5%
5. Carbon Dioxide 26%
6. Carbonate Dehydratase 15%
7. Carbonate Dehydratase Inhibitor 5%
8. Carbonate Dehydratase IX 100%
9. Carcinogen 5%
10. Catenin 5%
11. Dicarbonate 15%
12. Dimer 5%
13. Diseases 5%
14. Drug Discovery 10%
15. Drug Interaction 5%
16. Elemental Analysis 10%
17. Enzyme Inhibition 5%
18. Human Immunodeficiency Virus 1 5%
19. Hydration 10%
20. Hypoxia 10%
21. Infectious Agent 5%
22. Ionic Strength 5%
23. Isoenzyme 5%
24. Isoquinoline 5%
25. Isothiocyanate 5%
26. Lead Compound 10%
27. Malignant Neoplasm 26%
28. Neoplasm 63%
29. Pharmaceutical Chemistry 10%
30. Piperazine Derivative 5%
31. Porphyromonas gingivalis 5%
32. Prevalence 5%
33. Proteinase 5%
34. Pyrimidine 5%
35. Quinazoline 10%
36. Streptococcus mutans 5%
37. Structure Activity Relationship 15%
38. Structure-Based Drug Design 5%
39. Sulfonamide 21%
40. Therapeutic Use 5%
41. Thiol 5%
42. Triethylamine 10%
43. Tumor Microenvironment 5%
44. Tumor Model 10%