Novel QuinazolinoneBased Carbonic Anhydrase IX Inhibitors (CAI IX) as Potential Antitumor Agents

Pharmacology, Toxicology and Pharmaceutical Science

1. Carbonate Dehydratase IX 100%
2. Neoplasm 63%
3. Malignant Neoplasm 26%
4. Carbon Dioxide 26%
5. Sulfonamide 21%
6. Dicarbonate 15%
7. Structure Activity Relationship 15%
8. Carbonate Dehydratase 15%
9. Base 15%
10. Quinazoline 10%
11. Hypoxia 10%
12. Buffer 10%
13. Lead Compound 10%
14. Drug Discovery 10%
15. Triethylamine 10%
16. Tumor Model 10%
17. Hydration 10%
18. Pharmaceutical Chemistry 10%
19. Elemental Analysis 10%
20. Isothiocyanate 5%
21. Tumor Microenvironment 5%
22. Streptococcus mutans 5%
23. Isoquinoline 5%
24. Infectious Agent 5%
25. Proteinase 5%
26. Ionic Strength 5%
27. Therapeutic Use 5%
28. Isoenzyme 5%
29. Carcinogen 5%
30. Catenin 5%
31. Pyrimidine 5%
32. Diseases 5%
33. Human Immunodeficiency Virus 1 5%
34. Carbonate Dehydratase Inhibitor 5%
35. Porphyromonas gingivalis 5%
36. Prevalence 5%
37. Antitumor Activity 5%
38. Thiol 5%
39. Drug Interaction 5%
40. Enzyme Inhibition 5%
41. Cancer Incidence 5%
42. Dimer 5%
43. Piperazine Derivative 5%
44. Structure-Based Drug Design 5%