Water-mediated synthesis of disubstituted 5-aminopyrimidines from vinyl azides under microwave irradiation

Oussama Dehbi; Esam A. Ishak; Mohammed A. Bakht; Mohammed H. Geesi; Mohammed B. Alshammari; Vincent Chagnault; Abdellah Kaiba; Saïd Lazar; Yassine Riadi

doi:10.1080/17518253.2018.1437225

Water-mediated synthesis of disubstituted 5-aminopyrimidines from vinyl azides under microwave irradiation

Oussama Dehbi
, Esam A. Ishak
, Mohammed A. Bakht
, Mohammed H. Geesi
, Mohammed B. Alshammari
, Vincent Chagnault
, Abdellah Kaiba
, Saïd Lazar
, Yassine Riadi

Research output: Contribution to journal › Letter › peer-review

22 Scopus citations

Abstract

An efficient and ecofriendly method for the synthesis of disubstituted 5-aminopyrimidines from vinyl azides and urea or thiourea was developed. This reaction proceeds under microwave irradiation conditions in the presence of water as a solvent. The remarkable features of this new protocol are high conversion, short reaction times, cleaner reaction profiles and straightforward procedure.

Original language	English
Pages (from-to)	62-66
Number of pages	5
Journal	Green Chemistry Letters and Reviews
Volume	11
Issue number	2
DOIs	https://doi.org/10.1080/17518253.2018.1437225
State	Published - 3 Apr 2018

Keywords

disubstituted 5-aminopyrimidines
Green chemistry
microwaves
vinyl azide
water

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10.1080/17518253.2018.1437225

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title = "Water-mediated synthesis of disubstituted 5-aminopyrimidines from vinyl azides under microwave irradiation",

abstract = "An efficient and ecofriendly method for the synthesis of disubstituted 5-aminopyrimidines from vinyl azides and urea or thiourea was developed. This reaction proceeds under microwave irradiation conditions in the presence of water as a solvent. The remarkable features of this new protocol are high conversion, short reaction times, cleaner reaction profiles and straightforward procedure.",

keywords = "disubstituted 5-aminopyrimidines, Green chemistry, microwaves, vinyl azide, water",

author = "Oussama Dehbi and Ishak, \{Esam A.\} and Bakht, \{Mohammed A.\} and Geesi, \{Mohammed H.\} and Alshammari, \{Mohammed B.\} and Vincent Chagnault and Abdellah Kaiba and Sa{\"i}d Lazar and Yassine Riadi",

note = "Publisher Copyright: {\textcopyright} 2018 The Author(s). Published by Informa UK Limited, trading as Taylor \& Francis Group.",

year = "2018",

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doi = "10.1080/17518253.2018.1437225",

language = "English",

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journal = "Green Chemistry Letters and Reviews",

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TY - JOUR

T1 - Water-mediated synthesis of disubstituted 5-aminopyrimidines from vinyl azides under microwave irradiation

AU - Dehbi, Oussama

AU - Ishak, Esam A.

AU - Bakht, Mohammed A.

AU - Geesi, Mohammed H.

AU - Alshammari, Mohammed B.

AU - Chagnault, Vincent

AU - Kaiba, Abdellah

AU - Lazar, Saïd

AU - Riadi, Yassine

PY - 2018/4/3

Y1 - 2018/4/3

N2 - An efficient and ecofriendly method for the synthesis of disubstituted 5-aminopyrimidines from vinyl azides and urea or thiourea was developed. This reaction proceeds under microwave irradiation conditions in the presence of water as a solvent. The remarkable features of this new protocol are high conversion, short reaction times, cleaner reaction profiles and straightforward procedure.

AB - An efficient and ecofriendly method for the synthesis of disubstituted 5-aminopyrimidines from vinyl azides and urea or thiourea was developed. This reaction proceeds under microwave irradiation conditions in the presence of water as a solvent. The remarkable features of this new protocol are high conversion, short reaction times, cleaner reaction profiles and straightforward procedure.

KW - disubstituted 5-aminopyrimidines

KW - Green chemistry

KW - microwaves

KW - vinyl azide

KW - water

UR - https://www.scopus.com/pages/publications/85042710826

U2 - 10.1080/17518253.2018.1437225

DO - 10.1080/17518253.2018.1437225

M3 - Letter

AN - SCOPUS:85042710826

SN - 1751-8253

VL - 11

SP - 62

EP - 66

JO - Green Chemistry Letters and Reviews

JF - Green Chemistry Letters and Reviews

IS - 2

ER -

Water-mediated synthesis of disubstituted 5-aminopyrimidines from vinyl azides under microwave irradiation

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Keywords

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