Ultrasonic-Mediated Green Synthesis of Novel S-Arylated-Pyridopyrimidines and Antimicrobial Evaluation against Escherichia coli and Staphylococcus aureus

Yassine Riadi; Obaid Afzal; Abdul Malek S. Al-Tamimi; Abuzer Ali; Amena Ali

doi:10.1080/10406638.2021.1984953

Ultrasonic-Mediated Green Synthesis of Novel S-Arylated-Pyridopyrimidines and Antimicrobial Evaluation against Escherichia coli and Staphylococcus aureus

Yassine Riadi, Obaid Afzal, Abdul Malek S. Al-Tamimi, Abuzer Ali, Amena Ali

Pharmaceutical Chemistry

Taif University

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A facile, eco-friendly and effective ultrasonic strategy to synthesize S-arylated-pyridopyrimidines is described starting from 4-thiol or 4-halogenopyridopyrimidines through a reaction involving a green procedure under ultrasonic irradiation and in presence of water as green solvent. The resulted derivatives were assessed for the antibacterial activity against different bacteria strains.

Original language	English
Pages (from-to)	6546-6553
Number of pages	8
Journal	Polycyclic Aromatic Compounds
Volume	42
Issue number	9
DOIs	https://doi.org/10.1080/10406638.2021.1984953
State	Published - 2022

Keywords

Antibacterial activity
green
S-arylated-pyrido[2,3-d]pyrimidines
ultrasonic irradiation
water

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10.1080/10406638.2021.1984953

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abstract = "A facile, eco-friendly and effective ultrasonic strategy to synthesize S-arylated-pyridopyrimidines is described starting from 4-thiol or 4-halogenopyridopyrimidines through a reaction involving a green procedure under ultrasonic irradiation and in presence of water as green solvent. The resulted derivatives were assessed for the antibacterial activity against different bacteria strains.",

keywords = "Antibacterial activity, green, S-arylated-pyrido[2,3-d]pyrimidines, ultrasonic irradiation, water",

author = "Yassine Riadi and Obaid Afzal and Al-Tamimi, \{Abdul Malek S.\} and Abuzer Ali and Amena Ali",

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AU - Riadi, Yassine

AU - Afzal, Obaid

AU - Al-Tamimi, Abdul Malek S.

AU - Ali, Abuzer

AU - Ali, Amena

PY - 2022

Y1 - 2022

N2 - A facile, eco-friendly and effective ultrasonic strategy to synthesize S-arylated-pyridopyrimidines is described starting from 4-thiol or 4-halogenopyridopyrimidines through a reaction involving a green procedure under ultrasonic irradiation and in presence of water as green solvent. The resulted derivatives were assessed for the antibacterial activity against different bacteria strains.

AB - A facile, eco-friendly and effective ultrasonic strategy to synthesize S-arylated-pyridopyrimidines is described starting from 4-thiol or 4-halogenopyridopyrimidines through a reaction involving a green procedure under ultrasonic irradiation and in presence of water as green solvent. The resulted derivatives were assessed for the antibacterial activity against different bacteria strains.

KW - Antibacterial activity

KW - green

KW - S-arylated-pyrido[2,3-d]pyrimidines

KW - ultrasonic irradiation

KW - water

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DO - 10.1080/10406638.2021.1984953

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EP - 6553

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IS - 9

ER -

Ultrasonic-Mediated Green Synthesis of Novel S-Arylated-Pyridopyrimidines and Antimicrobial Evaluation against Escherichia coli and Staphylococcus aureus

Abstract

Keywords

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