Training neural networks as experimental models: Classifying biomedical datasets for sickle cell disease

  • Mohammed Khalaf
  • , Abir Jaafar Hussain
  • , Dhiya Al-Jumeily
  • , Robert Keight
  • , Russell Keenan
  • , Paul Fergus
  • , Haya Al-Askar
  • , Andy Shaw
  • , Ibrahim Olatunji Idowu

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

9 Scopus citations

Abstract

This paper discusses the use of various type of neural network architectures for the classification of medical data. Extensive research has indicated that neural networks generate significant improvements when used for the preprocessing of medical time-series data signals and have assisted in obtaining high accuracy in the classification of medical data. Up to date, most of hospitals and healthcare sectors in the United Kingdom are using manual approach for analysing patient input for sickle cell disease, which depends on clinician’s experience that can lead to time consuming and stress to patients. The results obtained froma range of models during our experiments have shown that the proposed Back-propagation trained feed-forward neural network classifier generated significantly better outcomes over the other range of classifiers. Using the Receiver Operating Characteristic curve, experiments results showed the following outcomes for our models, in order of best to worst: Back-propagation trained feed-forward neural net classifier: 0.989, Functional Link Neural Network: 0.972, in comparison to the Radial basis neural Network Classifiers with areas of 0.875, and the Voted Perception classifier: 0.766. A Linear Neural Network was used as baseline classifier to illustrate the importance of the previous models, producing an area of 0.849, followed by a random guessing model with an area of 0.524.

Original languageEnglish
Title of host publicationIntelligent Computing Theories and Application - 12th International Conference, ICIC 2016, Proceedings
EditorsPrashan Premaratne, De-Shuang Huang, Vitoantonio Bevilacqua
PublisherSpringer Verlag
Pages784-795
Number of pages12
ISBN (Print)9783319422909
DOIs
StatePublished - 2016
Event12th International Conference on Intelligent Computing Theories and Application, ICIC 2016 - Lanzhou, China
Duration: 2 Aug 20165 Aug 2016

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume9771
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference12th International Conference on Intelligent Computing Theories and Application, ICIC 2016
Country/TerritoryChina
CityLanzhou
Period2/08/165/08/16

Keywords

  • e-Health
  • Neural network architectures
  • Real datasets
  • Receiver operating characteristic curve
  • Sickle cell disease
  • The area under curve

Fingerprint

Dive into the research topics of 'Training neural networks as experimental models: Classifying biomedical datasets for sickle cell disease'. Together they form a unique fingerprint.

Cite this