Synthesis of some new 3, 5-bis (substituted) pyrazoles and isoxazoles based on (N′1E, N′3E)- N′1, N′3-bis (3, 4, 5-substitutedbenzlidene) malonohydrazide under solvothermal conditions

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Abstract

The new 3,5-(substituted) pyrazoles and isoxazoles were prepared by reaction of (N′1E , N′3E)- N′1, N′3-bis (3,4,5-substitutedbenzylidene) malonohydrazide with hydrazine hydrate and hydroxylamine hydrochloride respectively under solvothermal conditions involving an ecofriendly method without any environmental pollution, the yield are in the range of 75-96%. The structure of the new compounds were established using elemental analysis, IR, 1H NMR, 13C NMR.

Original languageEnglish
Pages (from-to)45-48
Number of pages4
JournalInternational Journal of Biomedical Science
Volume6
Issue number1
DOIs
StatePublished - 15 Mar 2010
Externally publishedYes

Keywords

  • Isoxazoles
  • Pyrazoles
  • Solvothermal

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