Synthesis of novel functionally substituted pyridazines and oxazines

M. Hammouda; Z. M.Abou Zeid; M. A. Metwally

Synthesis of novel functionally substituted pyridazines and oxazines

M. Hammouda, Z. M.Abou Zeid, M. A. Metwally

Mansoura University

Research output: Contribution to journal › Article › peer-review

Abstract

Acetone 1,3-di(phenylhydrazone) reacts with arylidenemalononitriles in the presence of piperidine to give the coressponding 3,3′- carbonylbispyridazine derivatives. Under the same reaction conditions dioxime reacts with arylidenemalononitriles to give the corresponding 3,3′-carbonylbis-1,2-oxazines. Dioxime reacts with primary aromatic amines and formalin in a molar ratio of 1:1:2 to give 1-arylidene-3,5-dihydroxyimino- piperidine-4-ones.

Original language	English
Pages (from-to)	1223-1229
Number of pages	7
Journal	Khimiya Geterotsiklicheskikh Soedinenii
Issue number	8
State	Published - 2008
Externally published	Yes

Keywords

1,2-dioximes
Acetone 1,3-dioxime
Acetone 1,3-diphenylhydrazone
Pyridazines

Cite this

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title = "Synthesis of novel functionally substituted pyridazines and oxazines",

abstract = "Acetone 1,3-di(phenylhydrazone) reacts with arylidenemalononitriles in the presence of piperidine to give the coressponding 3,3′- carbonylbispyridazine derivatives. Under the same reaction conditions dioxime reacts with arylidenemalononitriles to give the corresponding 3,3′-carbonylbis-1,2-oxazines. Dioxime reacts with primary aromatic amines and formalin in a molar ratio of 1:1:2 to give 1-arylidene-3,5-dihydroxyimino- piperidine-4-ones.",

keywords = "1,2-dioximes, Acetone 1,3-dioxime, Acetone 1,3-diphenylhydrazone, Pyridazines",

author = "M. Hammouda and Zeid, \{Z. M.Abou\} and Metwally, \{M. A.\}",

year = "2008",

language = "English",

pages = "1223--1229",

journal = "Khimiya Geterotsiklicheskikh Soedinenii",

issn = "0132-6244",

publisher = "Latvian Institute of Organic Synthesis",

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T1 - Synthesis of novel functionally substituted pyridazines and oxazines

AU - Hammouda, M.

AU - Zeid, Z. M.Abou

AU - Metwally, M. A.

PY - 2008

Y1 - 2008

N2 - Acetone 1,3-di(phenylhydrazone) reacts with arylidenemalononitriles in the presence of piperidine to give the coressponding 3,3′- carbonylbispyridazine derivatives. Under the same reaction conditions dioxime reacts with arylidenemalononitriles to give the corresponding 3,3′-carbonylbis-1,2-oxazines. Dioxime reacts with primary aromatic amines and formalin in a molar ratio of 1:1:2 to give 1-arylidene-3,5-dihydroxyimino- piperidine-4-ones.

AB - Acetone 1,3-di(phenylhydrazone) reacts with arylidenemalononitriles in the presence of piperidine to give the coressponding 3,3′- carbonylbispyridazine derivatives. Under the same reaction conditions dioxime reacts with arylidenemalononitriles to give the corresponding 3,3′-carbonylbis-1,2-oxazines. Dioxime reacts with primary aromatic amines and formalin in a molar ratio of 1:1:2 to give 1-arylidene-3,5-dihydroxyimino- piperidine-4-ones.

KW - 1,2-dioximes

KW - Acetone 1,3-dioxime

KW - Acetone 1,3-diphenylhydrazone

KW - Pyridazines

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M3 - Article

AN - SCOPUS:55949134961

SN - 0132-6244

SP - 1223

EP - 1229

JO - Khimiya Geterotsiklicheskikh Soedinenii

JF - Khimiya Geterotsiklicheskikh Soedinenii

IS - 8

ER -

Synthesis of novel functionally substituted pyridazines and oxazines

Abstract

Keywords

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