Synthesis and Anti-HIV Activity of Poly-Heterocyclic Compounds Containing Quinoline Moiety

Farag A. El-Essawy; Noora T.G. Ali; Nader M. Boshta

doi:10.1134/S1070363222060263

Synthesis and Anti-HIV Activity of Poly-Heterocyclic Compounds Containing Quinoline Moiety

Farag A. El-Essawy, Noora T.G. Ali, Nader M. Boshta

General

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Abstract: A novel series of poly-heterocyclic compounds containing quinoline as antiviral agents against HIV have been designed and synthesized. Structures of these novel derivatives have been confirmed by IR, NMR, and EI-MS spectra. Most of the products have been tested for their HIV inhibitory activity and characterized by high to moderate activity.

Original language	English
Pages (from-to)	1129-1136
Number of pages	8
Journal	Russian Journal of General Chemistry
Volume	92
Issue number	6
DOIs	https://doi.org/10.1134/S1070363222060263
State	Published - Jun 2022

Keywords

1,3,4-oxadiazole
antiviral activity
cyclocondensation
polyheterocyclic
quinoline
tetrazole

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1134/S1070363222060263

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title = "Synthesis and Anti-HIV Activity of Poly-Heterocyclic Compounds Containing Quinoline Moiety",

abstract = "Abstract: A novel series of poly-heterocyclic compounds containing quinoline as antiviral agents against HIV have been designed and synthesized. Structures of these novel derivatives have been confirmed by IR, NMR, and EI-MS spectra. Most of the products have been tested for their HIV inhibitory activity and characterized by high to moderate activity.",

keywords = "1,3,4-oxadiazole, antiviral activity, cyclocondensation, polyheterocyclic, quinoline, tetrazole",

author = "El-Essawy, \{Farag A.\} and Ali, \{Noora T.G.\} and Boshta, \{Nader M.\}",

note = "Publisher Copyright: {\textcopyright} 2022, Pleiades Publishing, Ltd.",

year = "2022",

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doi = "10.1134/S1070363222060263",

language = "English",

volume = "92",

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TY - JOUR

T1 - Synthesis and Anti-HIV Activity of Poly-Heterocyclic Compounds Containing Quinoline Moiety

AU - El-Essawy, Farag A.

AU - Ali, Noora T.G.

AU - Boshta, Nader M.

PY - 2022/6

Y1 - 2022/6

N2 - Abstract: A novel series of poly-heterocyclic compounds containing quinoline as antiviral agents against HIV have been designed and synthesized. Structures of these novel derivatives have been confirmed by IR, NMR, and EI-MS spectra. Most of the products have been tested for their HIV inhibitory activity and characterized by high to moderate activity.

AB - Abstract: A novel series of poly-heterocyclic compounds containing quinoline as antiviral agents against HIV have been designed and synthesized. Structures of these novel derivatives have been confirmed by IR, NMR, and EI-MS spectra. Most of the products have been tested for their HIV inhibitory activity and characterized by high to moderate activity.

KW - 1,3,4-oxadiazole

KW - antiviral activity

KW - cyclocondensation

KW - polyheterocyclic

KW - quinoline

KW - tetrazole

UR - http://www.scopus.com/inward/record.url?scp=85133648804&partnerID=8YFLogxK

U2 - 10.1134/S1070363222060263

DO - 10.1134/S1070363222060263

M3 - Article

AN - SCOPUS:85133648804

SN - 1070-3632

VL - 92

SP - 1129

EP - 1136

JO - Russian Journal of General Chemistry

JF - Russian Journal of General Chemistry

IS - 6

ER -

Synthesis and Anti-HIV Activity of Poly-Heterocyclic Compounds Containing Quinoline Moiety

Abstract

Keywords

UN SDGs

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