Solvent extraction, spectral analysis and antibacterial activity of the bioactive crystals of Sargassum aquifolium (Turner) C.Agardh from Red Sea

Sivakumar Sivagurunathan Moni; Mohammad Firoz Alam; Hafiz A. Makeen; Hassan A. Alhazmi; Muhammad Sultan; Rahimullah Siddiqui; Aamena Jabeen; Syeda Sanobar; Md Shamsher Alam; Zia Ur Rehman; Mohamed Eltyep Elmobark; Osama Madkhali; Anzarul Haque; Mohammed Albratty

doi:10.1080/14786419.2019.1645659

Solvent extraction, spectral analysis and antibacterial activity of the bioactive crystals of Sargassum aquifolium (Turner) C.Agardh from Red Sea

Sivakumar Sivagurunathan Moni
, Mohammad Firoz Alam
, Hafiz A. Makeen
, Hassan A. Alhazmi
, Muhammad Sultan
, Rahimullah Siddiqui
, Aamena Jabeen
, Syeda Sanobar
, Md Shamsher Alam
, Zia Ur Rehman
, Mohamed Eltyep Elmobark
, Osama Madkhali
, Anzarul Haque
, Mohammed Albratty

Pharmaceutics

Jazan University

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

The purpose of this study was to investigate the chemical composition and anti-bacterial properties of the bioactive principles of Sargassum aquifolium (Turner) C.Agardh, a brown seaweed in Red sea of Jazan province, Kingdom of Saudi Arabia. Crystals were obtained from the petroleum ether extract of Sargassum aquifolium and subjected to chemical tests, FTIR spectroscopic analysis and NMR analysis to identify their chemical composition, and to study their antibacterial properties against selected human pathogenic bacteria. In addition, GC–MS analysis was performed to identify the bioactive compounds in the crude petroleum ether extract. Results of the antibacterial effect of the crystal analyte showed a wide spectrum of activity against the screened human pathogenic bacteria.

Original language	English
Pages (from-to)	1379-1383
Number of pages	5
Journal	Natural Product Research
Volume	35
Issue number	8
DOIs	https://doi.org/10.1080/14786419.2019.1645659
State	Published - 2021

Keywords

Red sea
antibacterial
brown alga
crystals
phyto constituents
saponins
tannins

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10.1080/14786419.2019.1645659

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Moni, S. S., Alam, M. F., Makeen, H. A., Alhazmi, H. A., Sultan, M., Siddiqui, R., Jabeen, A., Sanobar, S., Alam, M. S., Rehman, Z. U., Elmobark, M. E., Madkhali, O., Haque, A., & Albratty, M. (2021). Solvent extraction, spectral analysis and antibacterial activity of the bioactive crystals of Sargassum aquifolium (Turner) C.Agardh from Red Sea. Natural Product Research, 35(8), 1379-1383. https://doi.org/10.1080/14786419.2019.1645659

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title = "Solvent extraction, spectral analysis and antibacterial activity of the bioactive crystals of Sargassum aquifolium (Turner) C.Agardh from Red Sea",

abstract = "The purpose of this study was to investigate the chemical composition and anti-bacterial properties of the bioactive principles of Sargassum aquifolium (Turner) C.Agardh, a brown seaweed in Red sea of Jazan province, Kingdom of Saudi Arabia. Crystals were obtained from the petroleum ether extract of Sargassum aquifolium and subjected to chemical tests, FTIR spectroscopic analysis and NMR analysis to identify their chemical composition, and to study their antibacterial properties against selected human pathogenic bacteria. In addition, GC–MS analysis was performed to identify the bioactive compounds in the crude petroleum ether extract. Results of the antibacterial effect of the crystal analyte showed a wide spectrum of activity against the screened human pathogenic bacteria.",

keywords = "Red sea, antibacterial, brown alga, crystals, phyto constituents, saponins, tannins",

author = "Moni, \{Sivakumar Sivagurunathan\} and Alam, \{Mohammad Firoz\} and Makeen, \{Hafiz A.\} and Alhazmi, \{Hassan A.\} and Muhammad Sultan and Rahimullah Siddiqui and Aamena Jabeen and Syeda Sanobar and Alam, \{Md Shamsher\} and Rehman, \{Zia Ur\} and Elmobark, \{Mohamed Eltyep\} and Osama Madkhali and Anzarul Haque and Mohammed Albratty",

note = "Publisher Copyright: {\textcopyright} 2019 Informa UK Limited, trading as Taylor \& Francis Group.",

year = "2021",

doi = "10.1080/14786419.2019.1645659",

language = "English",

volume = "35",

pages = "1379--1383",

journal = "Natural Product Research",

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publisher = "Taylor and Francis Ltd.",

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Moni, SS, Alam, MF, Makeen, HA, Alhazmi, HA, Sultan, M, Siddiqui, R, Jabeen, A, Sanobar, S, Alam, MS, Rehman, ZU, Elmobark, ME, Madkhali, O, Haque, A & Albratty, M 2021, 'Solvent extraction, spectral analysis and antibacterial activity of the bioactive crystals of Sargassum aquifolium (Turner) C.Agardh from Red Sea', Natural Product Research, vol. 35, no. 8, pp. 1379-1383. https://doi.org/10.1080/14786419.2019.1645659

TY - JOUR

T1 - Solvent extraction, spectral analysis and antibacterial activity of the bioactive crystals of Sargassum aquifolium (Turner) C.Agardh from Red Sea

AU - Moni, Sivakumar Sivagurunathan

AU - Alam, Mohammad Firoz

AU - Makeen, Hafiz A.

AU - Alhazmi, Hassan A.

AU - Sultan, Muhammad

AU - Siddiqui, Rahimullah

AU - Jabeen, Aamena

AU - Sanobar, Syeda

AU - Alam, Md Shamsher

AU - Rehman, Zia Ur

AU - Elmobark, Mohamed Eltyep

AU - Madkhali, Osama

AU - Haque, Anzarul

AU - Albratty, Mohammed

PY - 2021

Y1 - 2021

N2 - The purpose of this study was to investigate the chemical composition and anti-bacterial properties of the bioactive principles of Sargassum aquifolium (Turner) C.Agardh, a brown seaweed in Red sea of Jazan province, Kingdom of Saudi Arabia. Crystals were obtained from the petroleum ether extract of Sargassum aquifolium and subjected to chemical tests, FTIR spectroscopic analysis and NMR analysis to identify their chemical composition, and to study their antibacterial properties against selected human pathogenic bacteria. In addition, GC–MS analysis was performed to identify the bioactive compounds in the crude petroleum ether extract. Results of the antibacterial effect of the crystal analyte showed a wide spectrum of activity against the screened human pathogenic bacteria.

AB - The purpose of this study was to investigate the chemical composition and anti-bacterial properties of the bioactive principles of Sargassum aquifolium (Turner) C.Agardh, a brown seaweed in Red sea of Jazan province, Kingdom of Saudi Arabia. Crystals were obtained from the petroleum ether extract of Sargassum aquifolium and subjected to chemical tests, FTIR spectroscopic analysis and NMR analysis to identify their chemical composition, and to study their antibacterial properties against selected human pathogenic bacteria. In addition, GC–MS analysis was performed to identify the bioactive compounds in the crude petroleum ether extract. Results of the antibacterial effect of the crystal analyte showed a wide spectrum of activity against the screened human pathogenic bacteria.

KW - Red sea

KW - antibacterial

KW - brown alga

KW - crystals

KW - phyto constituents

KW - saponins

KW - tannins

UR - https://www.scopus.com/pages/publications/85070328023

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DO - 10.1080/14786419.2019.1645659

M3 - Article

C2 - 31368348

AN - SCOPUS:85070328023

SN - 1478-6419

VL - 35

SP - 1379

EP - 1383

JO - Natural Product Research

JF - Natural Product Research

IS - 8

ER -

Solvent extraction, spectral analysis and antibacterial activity of the bioactive crystals of Sargassum aquifolium (Turner) C.Agardh from Red Sea

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Keywords

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