SnS2nanosheets as next-generation artificial enzymes for colorimetric bio-sensing of L-cystine towards diabetic management and ease of inflammatory diseases

S. Mohanasundaram; S. Fathhoor Rabbani; Maruthi Rohit Ayyagari; Mohammad Javed Ansari; V. Sampath; Devvret Verma

doi:10.1063/5.0126202

SnS₂nanosheets as next-generation artificial enzymes for colorimetric bio-sensing of L-cystine towards diabetic management and ease of inflammatory diseases

S. Mohanasundaram, S. Fathhoor Rabbani, Maruthi Rohit Ayyagari, Mohammad Javed Ansari, V. Sampath, Devvret Verma

Pharmaceutics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Two-dimensional nanosheets (2D) have been emerged with novel aspect for the photo catalytic properties; it has drawn the significant interest for wide application. The catalytic property of SnS2 nanosheets was utilized as peroxidase mimicking for colorimetric bio-sensing of L-cystine towards diabetic management and ease of inflammatory diseases. The SnS2 behaves as artificial enzymes to catalyze the oxidative reaction over peroxidase substrate TMB in the existence of H2O2. The optimization study shows that the SnS2 nanosheets has noticeably superior affinity towards hydrogen peroxide (H2O2) and 3,3′,5,5′-tetramethylbenzidine (TMB). Moreover, colorimetric bio-sensing of L-cysteine has exhibited a higher selectivity and sensitivity by the peroxidase-like performance of SnS2. The larger surface and the semiconducting properties of SnS2 has makes it ideal candidate for the environmental and biomedicine applications.

Original language	English
Title of host publication	International Conference on Biomedical Engineering and Computing Technologies, ICBECT 2022
Publisher	American Institute of Physics Inc.
ISBN (Electronic)	9780735444430
DOIs	https://doi.org/10.1063/5.0126202
State	Published - 25 Apr 2023
Event	2022 International Conference on Biomedical Engineering and Computing Technologies, ICBECT 2022 - Chennai, India Duration: 21 Mar 2022 → 25 Mar 2022

Publication series

Name	AIP Conference Proceedings
Volume	2603
ISSN (Print)	0094-243X
ISSN (Electronic)	1551-7616

Conference

Conference	2022 International Conference on Biomedical Engineering and Computing Technologies, ICBECT 2022
Country/Territory	India
City	Chennai
Period	21/03/22 → 25/03/22

Keywords

Bio-sensor
L-cystine
SnS2
TMB
peroxidase mimics

Access to Document

10.1063/5.0126202

Cite this

Mohanasundaram, S., Rabbani, S. F., Ayyagari, M. R., Javed Ansari, M., Sampath, V., & Verma, D. (2023). SnS₂nanosheets as next-generation artificial enzymes for colorimetric bio-sensing of L-cystine towards diabetic management and ease of inflammatory diseases. In International Conference on Biomedical Engineering and Computing Technologies, ICBECT 2022 Article 040005 (AIP Conference Proceedings; Vol. 2603). American Institute of Physics Inc.. https://doi.org/10.1063/5.0126202

Mohanasundaram, S. ; Rabbani, S. Fathhoor ; Ayyagari, Maruthi Rohit et al. / SnS₂nanosheets as next-generation artificial enzymes for colorimetric bio-sensing of L-cystine towards diabetic management and ease of inflammatory diseases. International Conference on Biomedical Engineering and Computing Technologies, ICBECT 2022. American Institute of Physics Inc., 2023. (AIP Conference Proceedings).

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abstract = "Two-dimensional nanosheets (2D) have been emerged with novel aspect for the photo catalytic properties; it has drawn the significant interest for wide application. The catalytic property of SnS2 nanosheets was utilized as peroxidase mimicking for colorimetric bio-sensing of L-cystine towards diabetic management and ease of inflammatory diseases. The SnS2 behaves as artificial enzymes to catalyze the oxidative reaction over peroxidase substrate TMB in the existence of H2O2. The optimization study shows that the SnS2 nanosheets has noticeably superior affinity towards hydrogen peroxide (H2O2) and 3,3′,5,5′-tetramethylbenzidine (TMB). Moreover, colorimetric bio-sensing of L-cysteine has exhibited a higher selectivity and sensitivity by the peroxidase-like performance of SnS2. The larger surface and the semiconducting properties of SnS2 has makes it ideal candidate for the environmental and biomedicine applications.",

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Mohanasundaram, S, Rabbani, SF, Ayyagari, MR, Javed Ansari, M, Sampath, V & Verma, D 2023, SnS₂nanosheets as next-generation artificial enzymes for colorimetric bio-sensing of L-cystine towards diabetic management and ease of inflammatory diseases. in International Conference on Biomedical Engineering and Computing Technologies, ICBECT 2022., 040005, AIP Conference Proceedings, vol. 2603, American Institute of Physics Inc., 2022 International Conference on Biomedical Engineering and Computing Technologies, ICBECT 2022, Chennai, India, 21/03/22. https://doi.org/10.1063/5.0126202

SnS₂nanosheets as next-generation artificial enzymes for colorimetric bio-sensing of L-cystine towards diabetic management and ease of inflammatory diseases. / Mohanasundaram, S.; Rabbani, S. Fathhoor; Ayyagari, Maruthi Rohit et al.
International Conference on Biomedical Engineering and Computing Technologies, ICBECT 2022. American Institute of Physics Inc., 2023. 040005 (AIP Conference Proceedings; Vol. 2603).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AB - Two-dimensional nanosheets (2D) have been emerged with novel aspect for the photo catalytic properties; it has drawn the significant interest for wide application. The catalytic property of SnS2 nanosheets was utilized as peroxidase mimicking for colorimetric bio-sensing of L-cystine towards diabetic management and ease of inflammatory diseases. The SnS2 behaves as artificial enzymes to catalyze the oxidative reaction over peroxidase substrate TMB in the existence of H2O2. The optimization study shows that the SnS2 nanosheets has noticeably superior affinity towards hydrogen peroxide (H2O2) and 3,3′,5,5′-tetramethylbenzidine (TMB). Moreover, colorimetric bio-sensing of L-cysteine has exhibited a higher selectivity and sensitivity by the peroxidase-like performance of SnS2. The larger surface and the semiconducting properties of SnS2 has makes it ideal candidate for the environmental and biomedicine applications.

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Mohanasundaram S, Rabbani SF, Ayyagari MR, Javed Ansari M, Sampath V, Verma D. SnS₂nanosheets as next-generation artificial enzymes for colorimetric bio-sensing of L-cystine towards diabetic management and ease of inflammatory diseases. In International Conference on Biomedical Engineering and Computing Technologies, ICBECT 2022. American Institute of Physics Inc. 2023. 040005. (AIP Conference Proceedings). doi: 10.1063/5.0126202