Screening of medicinal phytocompounds with structure-based approaches to target key hotspot residues in tyrosyl-DNA phosphodiesterase 1: augmenting sensitivity of cancer cells to topoisomerase I inhibitors

Muhammad Suleman, Abbas Khan, Safir Ullah Khan, Mohammed Alissa, Suad A. Alghamdi, Amani Alghamdi, Abir Abdullah Alamro, Sergio Crovella

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Biochemistry, Genetics and Molecular Biology

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Pharmacology, Toxicology and Pharmaceutical Science