Regioselective palladium-catalyzed Suzuki–Miyaura coupling reaction of 2,4,6-trihalogenopyrido[2,3-d]pyrimidines

Yassine Riadi; Saïd Lazar; Gérald Guillaumet

doi:10.1016/j.crci.2019.01.006

Regioselective palladium-catalyzed Suzuki–Miyaura coupling reaction of 2,4,6-trihalogenopyrido[2,3-d]pyrimidines

Yassine Riadi
, Saïd Lazar
, Gérald Guillaumet

Pharmaceutical Chemistry

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

An effective, regioselective, and novel strategy to the access of 2,4,6-trisubstituted pyrido[2,3-d]pyrimidines is developed from the corresponding 2,4,6-trihalogenopyrido[2,3-d]pyrimidine through a Suzuki–Miyaura coupling reaction involving a novel regioselective halogen discrimination.

Original language	English
Pages (from-to)	294-298
Number of pages	5
Journal	Comptes Rendus Chimie
Volume	22
Issue number	4
DOIs	https://doi.org/10.1016/j.crci.2019.01.006
State	Published - Apr 2019

Keywords

Cross coupling
Pyridopyrimidines
Regioselective
Suzuki

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10.1016/j.crci.2019.01.006

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title = "Regioselective palladium-catalyzed Suzuki–Miyaura coupling reaction of 2,4,6-trihalogenopyrido[2,3-d]pyrimidines",

abstract = "An effective, regioselective, and novel strategy to the access of 2,4,6-trisubstituted pyrido[2,3-d]pyrimidines is developed from the corresponding 2,4,6-trihalogenopyrido[2,3-d]pyrimidine through a Suzuki–Miyaura coupling reaction involving a novel regioselective halogen discrimination.",

keywords = "Cross coupling, Pyridopyrimidines, Regioselective, Suzuki",

author = "Yassine Riadi and Sa{\"i}d Lazar and G{\'e}rald Guillaumet",

note = "Publisher Copyright: {\textcopyright} 2019 Acad{\'e}mie des sciences",

year = "2019",

month = apr,

doi = "10.1016/j.crci.2019.01.006",

language = "English",

volume = "22",

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T1 - Regioselective palladium-catalyzed Suzuki–Miyaura coupling reaction of 2,4,6-trihalogenopyrido[2,3-d]pyrimidines

AU - Riadi, Yassine

AU - Lazar, Saïd

AU - Guillaumet, Gérald

PY - 2019/4

Y1 - 2019/4

N2 - An effective, regioselective, and novel strategy to the access of 2,4,6-trisubstituted pyrido[2,3-d]pyrimidines is developed from the corresponding 2,4,6-trihalogenopyrido[2,3-d]pyrimidine through a Suzuki–Miyaura coupling reaction involving a novel regioselective halogen discrimination.

AB - An effective, regioselective, and novel strategy to the access of 2,4,6-trisubstituted pyrido[2,3-d]pyrimidines is developed from the corresponding 2,4,6-trihalogenopyrido[2,3-d]pyrimidine through a Suzuki–Miyaura coupling reaction involving a novel regioselective halogen discrimination.

KW - Cross coupling

KW - Pyridopyrimidines

KW - Regioselective

KW - Suzuki

UR - https://www.scopus.com/pages/publications/85061824446

U2 - 10.1016/j.crci.2019.01.006

DO - 10.1016/j.crci.2019.01.006

M3 - Article

AN - SCOPUS:85061824446

SN - 1631-0748

VL - 22

SP - 294

EP - 298

JO - Comptes Rendus Chimie

JF - Comptes Rendus Chimie

IS - 4

ER -

Regioselective palladium-catalyzed Suzuki–Miyaura coupling reaction of 2,4,6-trihalogenopyrido[2,3-d]pyrimidines

Abstract

Keywords

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