TY - JOUR
T1 - Recent progress in the chemistry of bicyclic 6–6 systems
T2 - chemistry of pyrido[1,2-a]pyrimidines
AU - Elattar, Khaled M.
AU - Rabie, Ramy
AU - Hammouda, Mohamed M.
N1 - Publisher Copyright:
© 2016, Springer-Verlag Wien.
PY - 2017/4/1
Y1 - 2017/4/1
N2 - Abstract: The present review provides a study on the structural features, reactions, and synthetic methodologies of pyrido[1,2-a]pyrimidines. Thus, the synthetic procedures and organic reactions since 2000 are described. The aim of this review is to give an overview of the diverse methodologies that have been reported on the chemistry of pyrido[1,2-a]pyrimidines. The tautomeric forms of 2-methyl-3-chloro-9-hydroxypyrido[1,2-a]pyrimidin-4-one are discussed, as well as, the biological importance and mechanistic pathways. Graphical abstract: [Figure not available: see fulltext.]
AB - Abstract: The present review provides a study on the structural features, reactions, and synthetic methodologies of pyrido[1,2-a]pyrimidines. Thus, the synthetic procedures and organic reactions since 2000 are described. The aim of this review is to give an overview of the diverse methodologies that have been reported on the chemistry of pyrido[1,2-a]pyrimidines. The tautomeric forms of 2-methyl-3-chloro-9-hydroxypyrido[1,2-a]pyrimidin-4-one are discussed, as well as, the biological importance and mechanistic pathways. Graphical abstract: [Figure not available: see fulltext.]
KW - Binary systems
KW - Pyrido[1,2-a]pyrimidines
KW - Reactions
KW - Synthesis of cyclic systems
KW - Tautomerism
KW - Tetracyclic systems
KW - Tricyclic systems
UR - http://www.scopus.com/inward/record.url?scp=84994309634&partnerID=8YFLogxK
U2 - 10.1007/s00706-016-1852-1
DO - 10.1007/s00706-016-1852-1
M3 - Review article
AN - SCOPUS:84994309634
SN - 0026-9247
VL - 148
SP - 601
EP - 627
JO - Monatshefte fur Chemie
JF - Monatshefte fur Chemie
IS - 4
ER -