Abstract
Ionic liquids (ILs) were identified to have a unique role in the pharmaceutical industry. ILs are defined as substances that almost entirely contain ions with a freezing point. A handful of these substances have drawn significant attention as pure, multipurpose solvents for a wide range of purposes. Ionic liquids exhibit a wide spectrum of chemical characteristics, as well as their potential for toxicity. Understanding of the components transmitting their cytotoxicity andbiological effectsarestill noticeably lacking. The thorough biophysical investigation of membrane contacts depicts ionic liquids, showing various side chains, cationic head groups, and also demonstrates variations in their binding to bilayers and impacts on lipid accumulation. Asthe ILsunder investigation show varying levels of biological activities and cytotoxicity, we shed more light on membrane interactions in this article as a potential significant factor underlying the biological differences in between compounds and provided a detailed analysis of theinteractions of membrane withnumerous Ionic liquids demonstrating different biological and structural properties. The impacts on lipid bilayers were also discussed in this research, and it was concluded that there was a connection between both the extent of membrane permeability or disruptionand the biological roles of the ionic liquids.
| Original language | English |
|---|---|
| Title of host publication | Ionic Liquids and their Application in Green Chemistry |
| Publisher | Elsevier |
| Pages | 113-136 |
| Number of pages | 24 |
| ISBN (Electronic) | 9780323959315 |
| ISBN (Print) | 9780323959322 |
| DOIs | |
| State | Published - 1 Jan 2023 |
| Externally published | Yes |
Keywords
- Biological activities
- Cytotoxicity
- Ionic liquids
- Pharmaceutical application
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