Pandemic Preparedness for COVID-19: Research, Healthcare, and Pharmaceutical Perspectives

  • Israel Mani
  • , Manikandan Bilal Nandakumar
  • , Amara Balan Balakrishnan
  • , Mohamudha Parveen Rahamathulla
  • , Mohan Pandi

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

The COVID-19 pandemic has highlighted the critical importance of pandemic preparedness worldwide, following the devastating 1918 pandemic. The rapid spread of COVID-19, originat-ing in China, led to its classification as a global pandemic by the World Health Organization. COVID-19 is a member of the Coronaviridae family, a large family of viruses that have undergone extensive mutation and evolution over time. Among the coronaviruses, SARS-CoV-2, a Beta-coronavirus, has emerged as a highly virulent pathogen capable of causing severe illness and fatali-ties in both humans and animals. Since 1966, various types of coronaviruses have surfaced, each exhibiting distinct mutations and structural characteristics. These genetic changes have contributed to the enhanced potency of the virus, intensifying the global pandemic crisis we face today. In response, the pharmaceutical approach to combat COVID-19 encompasses a multifaceted strategy. This in-cludes the development of novel antiviral drugs specifically targeting the virus, as well as the repur-posing of existing medications to evaluate their effectiveness against the virus. Additionally, there is a growing interest in exploring the potential of herbal and traditional medicine in the treatment of COVID-19. Continued research and collaboration among scientists, healthcare professionals, and pharmaceutical companies are crucial in the quest to find effective treatments for COVID-19 and to mitigate the impact of future coronavirus outbreaks. It is imperative to recognize the power and adaptability of microorganisms, emphasizing the need for vigilance and caution in preventing and managing infectious diseases. By investing in robust pandemic preparedness, measures and fostering global cooperation, we can enhance our ability to respond effectively to emerging viral threats and safeguard public health.

Original languageEnglish
Article numbere271023222887
Pages (from-to)74-86
Number of pages13
JournalCoronaviruses
Volume5
Issue number1
DOIs
StatePublished - 2024

Keywords

  • coronavirus
  • glycoprotein
  • herbal and traditional medicine
  • mutation
  • Pandemic
  • replication cycle

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